The pattern of plasma renin activity and aldosterone system in patients with sustained hydronephrosis

Abstract

Twenty-six patients with unilateral and bilateral hydronephrosis were subjected to investigation to identify the patterns of PRA-aldosterone system. The incidence of hypertension in the unilateral group was 28.5%, while in the bilateral group it was 50%; the overall incidence was 34.6%. In the hypertensive patients (9 cases), plasma renin activity and aldosterone were normal in one, and elevated in three. Aldosterone only was elevated in 3 cases, while PRA was elevated in 2. In the normotensive patients, the levels of PRA and aldosterone were normal in 5 patients, while in the remaining 12 cases one or both parameters were elevated.