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. 2020 Sep 16;17(18):6759.
doi: 10.3390/ijerph17186759.

Analysis of Low Cancer Mortality Rates in the Wine Regions of Tokaj and Balaton in Hungary

Sándor Sipka  1 , János Nagy  2 , Péter Sipka  3 , Judit Kocsis  4 , Judit Tóth  2 , Péter Árkosy  2 , Zsolt Horváth  4
Affiliations

Analysis of Low Cancer Mortality Rates in the Wine Regions of Tokaj and Balaton in Hungary

Sándor Sipka et al. Int J Environ Res Public Health. .

Abstract

The age-adjusted death rates (AADRs) due to cancers were investigated in two historical regions of white wines (Tokaj and Balaton) and in Hódmezővásárhely (HMV) as a control territory in Hungary between 2000 and 2010 evaluating 111,910 persons. The results of AADRs due to the eight most frequent types/gastrointestinal cancers were as follows: Tokaj 2120/664, Balaton: 2417/824, HMV: 2770/821, nationwide: 2773/887. The values found in Tokaj and Balaton regions were significantly less than those of HMV and nationwide. However, the least values were found in Tokaj. This Tokaj-related strong difference was not found among the regions in the case of young populations with hematological diseases but only in the older people who have been consuming their wines for decades. Supposedly, this wine-specific anti-cancer phenomenon could be related to the chemical differences existing in the two types of white wines, namely, to the pro-oxidant molecules of Tokaj wines derived from Botrytis cinerea. The roles of red meat consumption, hardness of drinking water, mineral content of soil, and socioeconomic status were negligible. It should be stressed that these data are valid only for these populations, for this period. Noteworthily, the different types of wines may have different effects on mortality rates during long-lasting consumptions.

Keywords: age-adjusted death rate; cancer; wines of Balaton; wines of Tokaj.

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Conflict of interest statement

The authors declare no conflict of interest.

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