Vasopressin Neurons: Master Integrators of Time and Homeostasis
- PMID: 32948352
- DOI: 10.1016/j.tins.2020.08.007
Vasopressin Neurons: Master Integrators of Time and Homeostasis
Abstract
A recent article by Gizowski and Bourque shows that vasopressinergic (VP) neurons within the suprachiasmatic nucleus (SCN) master circadian clock have the ability of encoding afferent input from osmosensors and generating appropriate homeostatic responses, suggesting that SCN neurons can integrate internal circadian time and acute changes in homeostatic markers.
Keywords: circadian; internal sensors; internal time; osmosensing; suprachiasmatic nucleus.
Copyright © 2020 Elsevier Ltd. All rights reserved.
Comment on
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Clock-driven vasopressin neurotransmission mediates anticipatory thirst prior to sleep.Nature. 2016 Sep 29;537(7622):685-8. doi: 10.1038/nature19756. Nature. 2016. PMID: 27680940
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