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. 2021 May;116(5):1196-1211.
doi: 10.1111/add.15269. Epub 2020 Oct 8.

England SimSmoke: the impact of nicotine vaping on smoking prevalence and smoking-attributable deaths in England

Affiliations

England SimSmoke: the impact of nicotine vaping on smoking prevalence and smoking-attributable deaths in England

David T Levy et al. Addiction. 2021 May.

Abstract

Background and aims: Whereas the use of nicotine vaping products (NVPs) is widespread, their impact on smoking prevalence is controversial. This study considered the potential impact of NVPs on smoking prevalence in England.

Design: Indirect simulation model. The England SimSmoke model is validated through 2012, before NVP use became more widely used by smokers. Because information on NVP-related transitions is limited, an indirect method is used; the difference in observed smoking prevalence (reflecting NVPs) is compared with a 2012-2019 counterfactual No-NVP scenario (without NVPs) to estimate the impact of NVPs on smoking and smoking-attributable deaths.

Setting: England, 2000-2019.

Participants: Nationally representative sample of population.

Measurements: England's population, mortality rates and smoking prevalence estimates from three national surveys and tobacco control policies.

Findings: Between 2000 and 2012, SimSmoke projected a decline in age 18+ smoking prevalence of 23.5% in men and 27.0% in women. These projections, as well as those by specific age groups, were generally consistent with findings from the three national surveys. Comparing 2012-2019 relative reduction in age 18+ prevalence from the Annual Population Survey (males, 27.5%) with the model-predicted No-NVP reduction (males, 7.3%), the implied NVP-attributable relative reduction in adult smoking prevalence was 20.2% (95% CI, 18.8%-22.0%) for males and 20.4% (18.7%-22.2%) for females. The NVP-attributable reduction was 27.2% (22.8%-31.6%) for males and 31.7% (27.4%-36.5%) for females ages 18-24 and 18.6% (15.2%-21.8%) for males and 15.0% (11.1%-18.8%) for females ages 25-34, with similar reductions for ages 35+. The implied reduction in smoking prevalence between 2012 and 2019 equates to 165 660 (132 453-199 501) averted deaths by 2052. Other surveys yielded smaller, but relatively consistent results.

Conclusions: An indirect method of simulation modelling indicates that substantial reductions in smoking prevalence occurred in England from 2012-2019 coinciding with the growth in nicotine vaping product use.

Keywords: E-cigarettes; England; public health; simulation model; smoking; vaping.

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Conflict of interest statement

Declaration of Interest

JB has received unrestricted research funding to study smoking cessation from companies who manufacture smoking cessation medications. JB declares no financial links with tobacco companies or e-cigarette manufacturers or their representatives. Other declare no conflict of interest.

Figures

Figure 1
Figure 1
England SimSmoke projections and policies, males and females, ages 16+, 2000–2019.

Comment in

References

    1. Farsalinos KE, Spyrou A, Tsimopoulou K, Stefopoulos C, Romagna G, Voudris V Nicotine absorption from electronic cigarette use: comparison between first and new-generation devices. Sci Rep 2014; 4: 4133. - PMC - PubMed
    1. Wagener TL, Floyd EL, Stepanov I, Driskill LM, Frank SG, Meier E, et al. Have combustible cigarettes met their match? The nicotine delivery profiles and harmful constituent exposures of second-generation and third-generation electronic cigarette users. Tob Control 2017; 26: e23–e28. - PMC - PubMed
    1. Glasser AM, Collins L, Pearson JL, Abudayyeh H, Niaura RS, Abrams DB, et al. Overview of electronic nicotine delivery systems: a systematic review. Am J Prev Med 2017; 52: e33–e66. - PMC - PubMed
    1. Levy DT, Yuan Z, Li Y, Mays D, Sanchez-Romero LM An examination of the variation in estimates of E-cigarette prevalence among U.S. adults. Int J Environ Res Public Health 2019Aug 30; 16: pii: E3164. - PMC - PubMed
    1. Marynak KL, Gammon DG, King BA, et al. National and state trends in sales of cigarettes and E-cigarettes, U.S., 2011-2015. Am J Prev Med 2017; 3: 96–101. - PMC - PubMed

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