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Comment
. 2020 Dec;43(12):933-935.
doi: 10.1016/j.tins.2020.09.002. Epub 2020 Sep 17.

This Is Your Brain on (Low) Glucose

Patrick Miller-Rhodes  1 , Harris A Gelbard  2 , Niccolò Terrando  3
Affiliations
Comment

This Is Your Brain on (Low) Glucose

Patrick Miller-Rhodes et al. Trends Neurosci. 2020 Dec.

Abstract

Brain functioning and high-order cognitive functions critically rely on glucose as a metabolic substrate. In a recent study, Kealy et al. investigated the impact of glucose availability on sickness behavior and delirium in mice and humans. They identified disrupted brain carbohydrate metabolism as a key mechanistic driver of these behaviors.

Keywords: delirium; hypoglycemia; lipopolysaccharide; neurodegeneration.

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References

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