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Review
. 2021 Mar;29(3):187-190.
doi: 10.1016/j.tim.2020.09.001. Epub 2020 Sep 18.

Bacterial Defense against the Type VI Secretion System

Sophie Robitaille  1 , Evan Trus  1 , Benjamin D Ross  2
Affiliations
Review

Bacterial Defense against the Type VI Secretion System

Sophie Robitaille et al. Trends Microbiol. 2021 Mar.

Abstract

Bacteria have evolved systems dedicated to interbacterial competition. Here we highlight defenses utilized by Gram-negative cells against type VI secretion system (T6SS)-wielding competitors, including physical barriers, genetically encoded antidotes, and stress responses. Further investigation of specific and general defenses will reveal the interbacterial selective pressures impacting bacterial survival in nature.

Keywords: exopolysaccharide; interbacterial defense; orphan immunity; peptidoglycan; stress responses; type VI secretion system.

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