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. 2020 May 4;54(Suppl 1):39-46.
doi: 10.1007/s43465-020-00127-1. eCollection 2020 Sep.

Quality of Life Evaluation Following Limb Lengthening Surgery in Patients with Achondroplasia

Sefa Giray Batıbay  1 , Halil İbrahim Balcı  2 , Serkan Bayram  2 , Mehmet Chodza  2 , Şeyda Göksoy  3 , Önder Murat Hürmeydan  4 , Aslı Derya Kardelen  5 , Cengiz Şen  2 , Mehmet Kocaoğlu  6
Affiliations

Quality of Life Evaluation Following Limb Lengthening Surgery in Patients with Achondroplasia

Sefa Giray Batıbay et al. Indian J Orthop. .

Abstract

Background: The primary objective of this study was to evaluate the quality of life following limb lengthening surgery in patients with achondroplasia. The complications and different lengthening techniques have and effects on mid-term results were also investigated.

Methods: We performed a retrospective, multicenter study by evaluating the records of patients with achondroplasia operated in our clinic between 1999 and 2014 for limb lengthening with a minimum follow-up of 3 years. Forty nine patients were underwent bilateral lower limb lengthening surgery and 21 of 49 patients underwent bilateral humerus lengthening surgery. Patients were evaluated by the Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core Scales to assess the health-related quality of life (HRQOL) of children. Twenty patients with achondroplasia who had no lengthening surgery history were also evaluated with the PedsQL score as the control group.

Results: The average age at the time of first surgery was 6.17 years. The average follow-up period was 100.2 months. The average age at the time of study 14.70 ± 2.44 (11-18) years. There were significant differences between the patients with humeral lengthening and patients who did not undergo humeral lengthening in all scores. Transient complications had minimal effects on scores. Although all scores in the operated group were higher than non-operated patients with achondroplasia, there were no significant differences.

Conclusion: Quality of life was significantly improved as a result of humerus lengthening surgery of patients with achondroplasia, despite minor complications compared with Lower limb lengthening surgery.

Level of evidence: Level III, case control study.

Keywords: Congenital femoral deficiency; Congenital short extremity; Congenital tibia pseudarthrosis; Lengthening rhythm; Quality of callus.

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Conflict of interest statement

Conflict of interestThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Fig. 1
Fig. 1
a Preoperative full-length weight-bearing lower-extremity radiograph of patients with achondroplasia. b Full-length weight-bearing lower-extremity radiograph of patients with simultaneous bilateral lengthening of femur and tibia. c Postoperative view of the patient
Fig. 2
Fig. 2
a Preoperative full-length weight-bearing lower-extremity radiographs of patients with achondroplasia. b X-Ray view of bilateral femoral lengthening the patients
Fig. 3
Fig. 3
a Preoperative bilateral humerus X-ray view, b, c Bilateral humeral lengthening view. d Postoperative bilateral humerus view of the patients
Fig. 4
Fig. 4
a–c Patients underwent simultaneous bilateral lengthening surgery
Fig. 5
Fig. 5
a This patient has regenerate fracture after removal of the fixator. b This patient was treated with Steinman pin
See this image and copyright information in PMC

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