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Case Reports
. 2020 Sep 2:8:2050313X20936034.
doi: 10.1177/2050313X20936034. eCollection 2020.

Recurrent melanoma development in a Caucasian female with CDKN2A+ mutation and FAMMM syndrome: A case report

Kaien Gu  1 , Rochelle Van De Velde  2   3 , Marshall Pitz  4 , Shane Silver  2   3
Affiliations
Case Reports

Recurrent melanoma development in a Caucasian female with CDKN2A+ mutation and FAMMM syndrome: A case report

Kaien Gu et al. SAGE Open Med Case Rep. .

Abstract

Melanoma is a form of skin cancer originating from melanocytes that has an increasing incidence over the past few decades. From 1992 to 2010, the overall incidence of melanoma was 12.29 cases per 100,000 person-years in Canada. Approximately 10% of cases are attributed to a hereditary component, with one of the most common being familial atypical multiple mole melanoma syndrome. In this case report, we highlight the atypical case of a middle-aged Caucasian female with familial atypical multiple mole melanoma syndrome, who has developed dozens of primary melanomas over the past decade. We highlight the management of her case, as well as the importance of monitoring by multiple other subspecialists given the propensity for the development of alternate malignancies.

Keywords: CDKN2A mutation; Familial atypical multiple mole melanoma syndrome; melanoma.

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Conflict of interest statement

Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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