Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Aug;8(15):963.
doi: 10.21037/atm.2020.03.154.

Percutaneous mitral repair: current and future devices

Affiliations
Review

Percutaneous mitral repair: current and future devices

Rodrigo Estévez-Loureiro et al. Ann Transl Med. 2020 Aug.

Abstract

Mitral regurgitation (MR) is the second most common valvular heart disease and its prevalence is increasing with population ageing. In the recent years we have witnessed the development of several transcatheter devices to correct MR in patients at high-risk for surgery. The majority of evidence regarding safety and efficacy of this new therapy comes from MitraClip studies. However, new alternatives on the field of valve repair have emerged with promising results. The aim of this review is to portrait the landscape of transcatheter mitral repair alternatives, from currently used devices to those that will have a role in the near future.

Keywords: Percutaneous mitral valve repair; heart failure; mitral regurgitation (MR); transcatheter.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/atm.2020.03.154). The series “Structural Heart Disease: The Revolution” was commissioned by the editorial office without any funding or sponsorship. REL has received research grant and speaker fees from Abbott Vascular. The authors have no other conflicts of interest to declare.

Figures

Figure 1
Figure 1
Current CE mark approved devices.
Figure 2
Figure 2
MitraClip device. (A) MitraClip XTR and NTR; (B) generation 4 (NTR, NTRW, XTR, XTRW). Reproduced with permission of Abbott Vascular (all rights reserved).
Figure 3
Figure 3
PASCAL device. Reproduced with permission.
Figure 4
Figure 4
New devices for transcatheter mitral valve repair. (A) Carillon; (B) Cardioband; (C) Mitralign; (D) Neochord; (E) Millipede IRIS (reproduced with permission of Boston Sci.); (F) ARTO device; (G) Amend ring. Reproduced with permission.

References

    1. Nkomo VT, Gardin JM, Skelton TN, et al. Burden of valvular heart diseases: a population-based study. Lancet 2006;368:1005-11. 10.1016/S0140-6736(06)69208-8 - DOI - PubMed
    1. Carpentier A. Cardiac valve surgery--the "French correction". J Thorac Cardiov Surg 1983;86:323-37. 10.1016/S0022-5223(19)39144-5 - DOI - PubMed
    1. Adams DH, Rosenhek R, Falk V. Degenerative mitral valve regurgitation: best practice revolution. Eur Heart J 2010;31:1958-66. 10.1093/eurheartj/ehq222 - DOI - PMC - PubMed
    1. Barlow JB, Pocock WA. The significance of late systolic murmurs and mid-late systolic clicks. Md State Med J 1963;12:76-7. - PubMed
    1. Bursi F, Barbieri A, Grigioni F, et al. Prognostic implications of functional mitral regurgitation according to the severity of the underlying chronic heart failure: a long-term outcome study. Eur J Heart Fail 2010;12:382-8. 10.1093/eurjhf/hfq014 - DOI - PubMed