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Comment
. 2020 Nov;25(11):1209.
doi: 10.1111/resp.13939. Epub 2020 Sep 20.

Severe COVID-19 and interleukin-6 receptor antagonist tocilizumab: Some notes of concern

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Comment

Severe COVID-19 and interleukin-6 receptor antagonist tocilizumab: Some notes of concern

Karolina Akinosoglou et al. Respirology. 2020 Nov.

Abstract

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    Savinelli S, McCarthy C, Mallon PW; All Ireland Infectious Diseases (AIID) Cohort Collaborators. Savinelli S, et al. Respirology. 2020 Nov;25(11):1210-1211. doi: 10.1111/resp.13940. Epub 2020 Sep 20. Respirology. 2020. PMID: 32954555 Free PMC article.

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References

    1. McCarthy C, Savinelli S, Feeney ER, Butler MW, O'Broin C, Ryan S, O'Neill L, Murphy DJ, Gallagher CG, McKone EF et al. Tocilizumab therapy in individuals with COVID‐19 infection and hyperinflammatory state. Respirology 2020; 25: 1090–4. - PMC - PubMed
    1. Keske Ş, Tekin S, Sait B, İrkören P, Kapmaz M, Çimen C, Uğur S, Çelebi I, Oğuzalp Bakır V, Palaoğlu E et al. Appropriate use of tocilizumab in COVID‐19 infection. Int. J. Infect. Dis. 2020; S1201‐9712(20):30580–4. 10.1016/j.ijid.2020.07.036. - DOI - PMC - PubMed
    1. Canziani LM, Trovati S, Brunetta E, Testa A, De Santis M, Bombardieri E, Guidelli G, Albano G, Folci M, Squadroni M et al.; Humanitas, Gavazzeni/Castelli C‐TF . Interleukin‐6 receptor blocking with intravenous tocilizumab in COVID‐19 severe acute respiratory distress syndrome: a retrospective case‐control survival analysis of 128 patients. J. Autoimmun. 2020. 10.1016/j.jaut.2020.102511. - DOI - PMC - PubMed
    1. Sheppard M, Laskou F, Stapleton PP, Hadavi S, Dasgupta B. Tocilizumab (Actemra). Hum. Vaccin. Immunother. 2017; 13: 1972–88. - PMC - PubMed