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Comment
. 2020 Aug;11(8):e00180.
doi: 10.14309/ctg.0000000000000180.

Power and Pitfalls of Computational Methods to Identify New Genes Responsible for Acute Liver Failure of Indeterminate Etiology in Adults

Affiliations
Comment

Power and Pitfalls of Computational Methods to Identify New Genes Responsible for Acute Liver Failure of Indeterminate Etiology in Adults

Abdelkader Heddar et al. Clin Transl Gastroenterol. 2020 Aug.

Erratum in

No abstract available

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Conflict of interest statement

Guarantor of the article: Micheline Misrahi, MD, PhD.

Specific author contribution: A.H. performed reanalysis and interpretation of published computational data and wrote the letter. M.M. supervised the study, wrote, and revised the manuscript.

Financial support: None to report.

Potential competing interests: None to report.

Comment in

Comment on

References

    1. Rakela J, Rule J, Ganger D, et al. Whole exome sequencing among 26 patients with indeterminate acute liver failure: A pilot study. Clin Transl Gastroenterol 2019;10:e00087. - PMC - PubMed
    1. Kopanos C, Tsiolkas V, Kouris A, et al. VarSome: The human genomic variant search engine. Bioinformatics 2019;35:1978–80. - PMC - PubMed
    1. Karczewski KJ, Francioli LC, Tiao G, et al. Variation across 141,456 human exomes and genomes reveals the spectrum of loss-of-function intolerance across human protein-coding genes. bioRxiv 2019:531210.
    1. Zhang ZD, Frankish A, Hunt T, et al. Identification and analysis of unitary pseudogenes: Historic and contemporary gene losses in humans and other primates. Genome Biol 2010;11:R26. - PMC - PubMed