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. 2020 Sep 1;57(5):333-339.
doi: 10.3928/01913913-20200804-01.

Development of Screening Criteria for Retinopathy of Prematurity in Ulaanbaatar, Mongolia, Using a Web-based Data Management System

Shelbi L Olson, Tsengelmaa Chuluunbat, Emily D Cole, Karyn E Jonas, Munkhuu Bayalag, Chimgee Chuluunkhuu, Nita G Valikodath, D Hunter Cherwek, Nathan Congdon, Leslie D MacKeen, Joelle Hallak, Vivien Yap, Susan Ostmo, Wei Chi Wu, J Peter Campbell, Michael F Chiang, R V Paul Chan

Development of Screening Criteria for Retinopathy of Prematurity in Ulaanbaatar, Mongolia, Using a Web-based Data Management System

Shelbi L Olson et al. J Pediatr Ophthalmol Strabismus. .

Abstract

Purpose: To describe a process for identifying birth weight (BW) and gestational age (GA) screening guidelines in Mongolia.

Methods: This was a prospective cohort study in a tertiary care hospital in Ulaanbataar, Mongolia, of 193 premature infants with GA of 36 weeks or younger and/or BW of 2,000 g or less) with regression analysis to determine associations between BW and GA and the development of retinopathy of prematurity (ROP).

Results: As BW and GA decreased, the relative risk of developing ROP increased. The relative risk of developing any stage of ROP in infants born at 29 weeks or younger was 2.91 (95% CI: 1.55 to 5.44; P < .001] compared to older infants. The relative risk of developing any type of ROP in infants with BW of less than 1,200 g was 2.41 (95% CI: 1.35 to 4.29; P = .003] and developing type 2 or worse ROP was 2.05 (95% CI: 0.99 to 4.25; P = .05).

Conclusions: Infants in Mongolia with heavier BW and older GA who fall outside of current United States screening guidelines of GA of 30 weeks or younger and/or BW of 1,500 g or less developed clinically relevant ROP. [J Pediatr Ophthalmol Strabismus. 2020;57(5):333-339.].

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Figures

Figure 1.
Figure 1.
Distribution of birth weight (BW) and gestational age (GA) in the cohort of patients analyzed.
Figure 2.
Figure 2.
An example of a patient who was treated with anti-vascular endothelial growth factor for aggressive posterior retinopathy of prematurity at post-menstrual age of 34 weeks. The patient’s gestational age was 29 weeks and birth weight was 1,250 g. The image on the left is a temporal view and the image on the right is the inferior view. Both images are from the same patient.
See this image and copyright information in PMC

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