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Observational Study
. 2020 Dec;33(6):444-447.
doi: 10.37201/req/077.2020. Epub 2020 Sep 22.

[Description of Influenza B in seasonal epidemic in Cantabria during the beginning of the pandemia due to SARS-CoV-2]

[Article in Spanish]
D Pablo-Marcos  1 , A Rodríguez-Fernández, M Gozalo, J Agüero, F Arnaiz de Las Revillas, J Calvo
Affiliations
Observational Study

[Description of Influenza B in seasonal epidemic in Cantabria during the beginning of the pandemia due to SARS-CoV-2]

[Article in Spanish]
D Pablo-Marcos et al. Rev Esp Quimioter. 2020 Dec.

Abstract
in English, Spanish

Objective: Co-circulation of the two Influenza B lineages hinders forecast of strain to include in trivalent vaccine. Autonomous Communities such as Cantabria continue without supplying tetravalent vaccine. The aim of this study was to analyse epidemiological characteristics of influenza type B in Cantabria (2019-2020 season) as well as to establish the predominant lineage and its relation to the recommended vaccine.

Methods: Retrospective study whereby flu diagnosis and lineage analysis were determined by RT-PCR.

Results: All samples belonged to the Victoria lineage. Most prevalent viral co-infection was due to SARS-CoV-2. The population affected by influenza B was mainly paediatric and non-vaccinated patients more frequently required hospital admittance.

Conclusions: Influenza type B has a higher incidence in the paediatric population and type A affects more the adult population. Only 28.8% of patients with Influenza B that presented with some underlying condition or risk factor were vaccinated. This shows the need to increase coverage with tetravalent vaccines in order to reduce the burden of disease associated with the Influenza B virus.

Introducción: La cocirculación de los dos linajes de gripe B dificulta la predicción de la cepa a incluir en la vacuna trivalente. Comunidades autónomas (CCAA) como Cantabria continúan sin suministrar la vacuna tetravalente. El objetivo de este estudio fue analizar las características epidemiológicas de la gripe B en Cantabria (temporada 2019-2020), y determinar el linaje predominante y su relación con la vacuna recomendada.

Métodos: Estudio retrospectivo en el que el diagnóstico de gripe y los linajes de gripe B se determinaron mediante RTPCR.

Resultados: Todas las muestras pertenecieron al linaje Victoria. La coinfección vírica más frecuente fue por SARSCoV-2. La población afectada por gripe B fue fundamental-mente pediátrica y los pacientes no vacunados requirieron más frecuentemente ingreso hospitalario.

Conclusión: La gripe B presenta una mayor incidencia sobre población pediátrica, y la gripe A afecta más a población adulta. Sólo el 28,8% de los pacientes con gripe B que presentaban algún factor de riesgo estaban vacunados, existiendo la necesidad de aumentar la cobertura con vacunas tetravalentes para reducir la carga de enfermedad asociada al virus gripal B.

Keywords: Influenza; epidemiology; vaccination.

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Conflict of interest statement

Los autores declaran no tener conflictos de intereses.

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References

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