Sex Determination: TRA-1 Is a Non-binary Regulator of Sexual Identity
- PMID: 32961156
- DOI: 10.1016/j.cub.2020.07.047
Sex Determination: TRA-1 Is a Non-binary Regulator of Sexual Identity
Abstract
In nematodes, TRA-1 represses the transcription of genes involved in male differentiation, allowing XX animals to undergo normal hermaphrodite development. New reports show that this transcription factor also acts in XO males, to control the differentiation of many neurons.
Copyright © 2020 Elsevier Inc. All rights reserved.
Comment on
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Temporal, Spatial, Sexual and Environmental Regulation of the Master Regulator of Sexual Differentiation in C. elegans.Curr Biol. 2020 Sep 21;30(18):3604-3616.e3. doi: 10.1016/j.cub.2020.06.060. Epub 2020 Jul 23. Curr Biol. 2020. PMID: 32707064
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Dynamic, Non-binary Specification of Sexual State in the C. elegans Nervous System.Curr Biol. 2020 Sep 21;30(18):3617-3623.e3. doi: 10.1016/j.cub.2020.07.007. Epub 2020 Jul 23. Curr Biol. 2020. PMID: 32707065 Free PMC article.
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