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Clinical Trial
. 1977;164(4):314-77.

[Psychopathometrical results of follow-up studies of trichloroethylene-exposed persons (author's transl)]

[Article in German]
  • PMID: 329621
Clinical Trial

[Psychopathometrical results of follow-up studies of trichloroethylene-exposed persons (author's transl)]

[Article in German]
G Triebig et al. Zentralbl Bakteriol Orig B. 1977.

Abstract

Seven clinical healthy volunteers were exposed to trichloroethylene concentration in air with 520 mg/m3 (100 ppm) at an average 6 hours a day on 5 consecutive days. Corresponding volunteers were exposed to a placebo for the same period. --The persons were examined psychopathometrically and biochemically at the beginning and after every day of exposure. The trichloroethylene-metabolites in blood and urine were dated in order to quantify the loads. --Purpose of the psychopathometrical testing methods was the observation, whether a psychological impairment in the sense of a "psychoorganic syndrome" may occur under these exposition-conditions. --Standardized achievement-tests and self-report rating scales were used in order to demonstrate reversible physical provable psychosis that may be possible. Comparing the psychopathometrical results of the exposed and non-exposed volunteers no statistical significant difference was visible in spite of the analytically proved considerable incorporation of the solvent.

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