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Review
. 2017 Sep 4;7(9):257.
doi: 10.3390/nano7090257.

Production and Status of Bacterial Cellulose in Biomedical Engineering

Mona Moniri  1   2 , Amin Boroumand Moghaddam  1   2 , Susan Azizi  1 , Raha Abdul Rahim  3 , Arbakariya Bin Ariff  1   4 , Wan Zuhainis Saad  5   6 , Mohammad Navaderi  7 , Rosfarizan Mohamad  1   6
Affiliations
Review

Production and Status of Bacterial Cellulose in Biomedical Engineering

Mona Moniri et al. Nanomaterials (Basel). .

Abstract

Bacterial cellulose (BC) is a highly pure and crystalline material generated by aerobic bacteria, which has received significant interest due to its unique physiochemical characteristics in comparison with plant cellulose. BC, alone or in combination with different components (e.g., biopolymers and nanoparticles), can be used for a wide range of applications, such as medical products, electrical instruments, and food ingredients. In recent years, biomedical devices have gained important attention due to the increase in medical engineering products for wound care, regeneration of organs, diagnosis of diseases, and drug transportation. Bacterial cellulose has potential applications across several medical sectors and permits the development of innovative materials. This paper reviews the progress of related research, including overall information about bacterial cellulose, production by microorganisms, mechanisms as well as BC cultivation and its nanocomposites. The latest use of BC in the biomedical field is thoroughly discussed with its applications in both a pure and composite form. This paper concludes the further investigations of BC in the future that are required to make it marketable in vital biomaterials.

Keywords: bacteria cellulose; bacteria nanocellulose; biosensors; scaffolds; wound dressing.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Advantages of bacterial cellulose.
Figure 2
Figure 2
Biosynthetic pathway of cellulose in the cells of microorganisms.
Figure 3
Figure 3
The process of purification of bacteria cellulose (BC) from G. xylinus.
Figure 4
Figure 4
The use of BC as a (A) matrix or (B) reinforcement to prepare nanocomposites.
Figure 5
Figure 5
Biomedical applications of BC.
Scheme 1
Scheme 1
Organic nanocomposites for wound healing.
Scheme 2
Scheme 2
BC impregnated with Ag nanoparticles for the wound dressing and interaction of Ag nanoparticles with bacteria cell pathogens.
See this image and copyright information in PMC

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