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Comment
. 2021 Jan;116(1):15-17.
doi: 10.1111/vox.13004. Epub 2020 Sep 23.

Blood group ABO polymorphism inhibits SARS-CoV-2 infection and affects COVID-19 progression

Fumiichiro Yamamoto  1 , Miyako Yamamoto  1 , Eduardo Muñiz-Diaz  2
Affiliations
Comment

Blood group ABO polymorphism inhibits SARS-CoV-2 infection and affects COVID-19 progression

Fumiichiro Yamamoto et al. Vox Sang. 2021 Jan.
No abstract available

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Figures

Fig. 1
Fig. 1
Differential inhibition of infection between SARS‐CoV‐2 viruses exhibiting different ABO phenotypes and individuals of groups A, B, AB and O.
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References

    1. Huang C, Wang Y, Li X, et al.: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395:497–506 - PMC - PubMed
    1. Centers for Disease Control and Prevention (CDC) : Coronavirus Disease 2019 (COVID‐19), People at Increased Risk for Severe Illness. Available online: https://www.cdc.gov/coronavirus/2019‐ncov/need‐extra‐precautions/index.html (accessed on 20 August 2020).
    1. Guillon P, Clément M, Sébille V, et al.: Inhibition of the interaction between the SARS‐CoV Spike protein and its cellular receptor by anti‐histo‐blood group antibodies. Glycobiology 2008; 18:1085–1093 - PMC - PubMed
    1. Arendrup M, Hansen JE, Clausen H, et al.: Antibody to histo‐blood group A antigen neutralizes HIV produced by lymphocytes from blood group A donors but not from blood group B or O donors. AIDS 1991; 5:441–444 - PubMed
    1. Preece AF, Strahan KM, Devitt J, et al.: Expression of ABO or related antigenic carbohydrates on viral envelopes leads to neutralization in the presence of serum containing specific natural antibodies and complement. Blood 2002; 99:2477–2482 - PubMed

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