Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Sep 21;66Suppl 2(Suppl 2):143-147.
doi: 10.1590/1806-9282.66.S2.143. eCollection 2020.

Sleep and immunity in times of COVID-19

Eduardo de Sousa Martins E Silva  1 , Ben Hur Vitor Silva Ono  2 , José Carlos Souza  3
Affiliations
Free article
Review

Sleep and immunity in times of COVID-19

Eduardo de Sousa Martins E Silva et al. Rev Assoc Med Bras (1992). .
Free article

Abstract

Background: Analyze how the COVID-19 (SARS-CoV-2) pandemic and its social restriction measures affect sleep quality and the immunological system.

Methods: An integrative bibliographical review was carried out using scientific articles from the last five years, from the PUBMED databases, with the descriptors: Sleep; Quarantine; COVID-19; Immunity; Mental Health. Besides the books "Oxford textbook of sleep disorders", "Cellular and molecular immunology", and "Treaty of Infectology".

Results: Sleep affects immunity. This happens through the regulation of immunological markers and their cells. Therefore, the COVID-19 pandemic can promote sleep disturbances and harm the immune system function.

Conclusion: Sleep exercises a direct influence on immunity maintenance and immunological response. Circadian rhythm alterations, associated with the psychological problems imposed by the COVID-19 pandemic compromise the quality of sleep and, for that reason, the immune system.

PubMed Disclaimer

LinkOut - more resources