Anatomy, Head and Neck: Carotid Bodies
- PMID: 32965908
- Bookshelf ID: NBK562237
Anatomy, Head and Neck: Carotid Bodies
Excerpt
The carotid body is a 2 to 6 mm, round bilateral sensory organ in the peripheral nervous system located in the adventitia of the bifurcation of the common carotid artery. These peripheral chemosensory cells play a vital, physiologic role in the human body as they maintain physiologic homeostasis and regulation of sustaining life. These sensory chemoreceptors act to detect chemical changes in the body through the interaction with surrounding arterial blood flow by monitoring blood gas tension and pH. Specifically, the carotid bodies can detect changes in the quality in the composition of arterial blood flow, such as pH, CO2, temperature, and partial pressure of arterial oxygen.
The effect in which these structures play an essential physiologic role is in their physiologic response following changes in the vasculature by signaling the rest of the peripheral nervous system. The carotid bodies also possess an interdependent regulatory relationship with other regulatory organs, such as the kidney.
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References
-
- Bee D, Howard P. The carotid body: a review of its anatomy, physiology and clinical importance. Monaldi Arch Chest Dis. 1993;48(1):48-53. - PubMed
-
- Fitzgerald RS, Eyzaguirre C, Zapata P. Fifty years of progress in carotid body physiology--invited article. Adv Exp Med Biol. 2009;648:19-28. - PubMed
-
- Prabhakar NR, Peng YJ. Peripheral chemoreceptors in health and disease. J Appl Physiol (1985) 2004 Jan;96(1):359-66. - PubMed
-
- Biscoe TJ. Carotid body: structure and function. Physiol Rev. 1971 Jul;51(3):437-95. - PubMed
-
- Grönblad M. Function and structure of the carotid body. Med Biol. 1983;61(5):229-48. - PubMed
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