Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Laryngeal Papillomas

Gabriel A. Rivera  1 , Fernando Morell  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Laryngeal Papillomas

Gabriel A. Rivera et al.
Free Books & Documents

Excerpt

Laryngeal papillomatosis (LP), also known as recurrent respiratory papillomatosis (RRP), is the most common benign mesenchymal neoplasm of the larynx in children. RRP is characterized by an over-proliferation of benign squamous papillomas in the aerodigestive tract. The condition has a childhood-onset type and an adult-onset type. It is one of the most difficult benign histologic conditions to treat due to its high tendency to recur and spread to the adjacent respiratory tract. This chapter will briefly discuss the etiology, clinical findings, diagnostic modalities, and the different surgical and nonsurgical management options, as well as recent preventive measures.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Gabriel Rivera declares no relevant financial relationships with ineligible companies.

Disclosure: Fernando Morell declares no relevant financial relationships with ineligible companies.

References

    1. Carifi M, Napolitano D, Morandi M, Dall'Olio D. Recurrent respiratory papillomatosis: current and future perspectives. Ther Clin Risk Manag. 2015;11:731-8. - PMC - PubMed
    1. Kashima HK, Kessis T, Mounts P, Shah K. Polymerase chain reaction identification of human papillomavirus DNA in CO2 laser plume from recurrent respiratory papillomatosis. Otolaryngol Head Neck Surg. 1991 Feb;104(2):191-5. - PubMed
    1. Derkay CS. Recurrent respiratory papillomatosis. Laryngoscope. 2001 Jan;111(1):57-69. - PubMed
    1. Larson DA, Derkay CS. Epidemiology of recurrent respiratory papillomatosis. APMIS. 2010 Jun;118(6-7):450-4. - PubMed
    1. Vambutas A, Di Lorenzo TP, Steinberg BM. Laryngeal papilloma cells have high levels of epidermal growth factor receptor and respond to epidermal growth factor by a decrease in epithelial differentiation. Cancer Res. 1993 Feb 15;53(4):910-4. - PubMed

Publication types

LinkOut - more resources