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. 2022 Feb 17;30(2):424-427.
doi: 10.1080/09273948.2020.1799036. Epub 2020 Sep 23.

Effect of Fundus Fluorescein Angiography on Semiautomated Aqueous Flare Measurements

Muhammad Sohail Halim  1   2 , Neil Onghanseng  1 , Jung Hyun Park  1 , Mervenur Yilmaz  3 , Asadu Segawa  3 , Mestan Ertop  3 , Muhammad Hassan  1 , Anh Nt Tran  1 , Zeynep Aktas  3 , Sengul Ozdek  3 , Gokhan Gurelik  3 , Diana V Do  1 , Yasir J Sepah  1 , Quan Dong Nguyen  1 , Murat Hasanreisoglu  1   3   4   5
Affiliations

Effect of Fundus Fluorescein Angiography on Semiautomated Aqueous Flare Measurements

Muhammad Sohail Halim et al. Ocul Immunol Inflamm. .

Abstract

Purpose: To evaluate the effects of fluorescein fundus angiography (FFA) on semiautomated aqueous flare measurements.

Methods: Laser flare photometer (LFP) measurements was performed at baseline, 30 min, and 4 h after the intravenous administration of sodium fluorescein dye. FFA was performed immediately after the baseline LFP measurement. LFP values at 30 min and 4 h after FFA were compared to baseline values. Mean change in LFP measurements at 30 min and 4 hafter baseline was compared between FFA arm and controls.

Results: The mean flare measurement in the FFA and control arm dropped 6% (p value = 0.002) and 9% (p value = 0.04), respectively. Mean change in LFP measurement at 30 min and 4 h after baseline was not significant between FFA arm and controls.

Conclusions: Administration of fluorescein dye does not increase LFP values. The decrease in the LFP measurement following FFA may be attributed to dilation drops.

Keywords: Laser flare photometry; aqueous flare; fluorescein angiography; uveitis.

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Conflict of interest statement

Declaration of Interest

None of the authors has conflict of interest with the submission. No financial support was received for this submission.

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