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. 2020 Sep 23;19(1):211.
doi: 10.1186/s12944-020-01388-3.

Elevated serum triglyceride predicts recurrence of colorectal polyps in patients with advanced adenomas

Boying Liu  1 , Pingwu Wen  1 , Xiaodong Gu  2 , Ruiqiang Weng  2 , Sudong Liu  3   4
Affiliations

Elevated serum triglyceride predicts recurrence of colorectal polyps in patients with advanced adenomas

Boying Liu et al. Lipids Health Dis. .

Abstract

Background: Recurrence of colorectal polyps is common and impacted by various factors. This study was performed to explore the association between lipid profiles and recurrence of colorectal polyps.

Methods: This study retrospectively analyzed the lipid profiles of 435 patients who underwent colonoscopy with removal of colorectal polyps and assessed recurrence of polyps by follow-up colonoscopy. Multivariate regression logistic analysis was used to evaluate the association between lipid profiles and polyp recurrence.

Results: During the 1.5-year follow-up, recurrence of colorectal polyps was observed in 135 of 435 patients (30.34%). Patients with recurrent polyps showed a higher level of triglycerides (P = 0.006) and lower levels of high-density lipoprotein cholesterol (P = 0.008) and apolipoprotein A1 (P = 0.033). The multivariate regression logistic model suggested that an elevated triglyceride level was an independent risk factor for polyp recurrence (odds ratio, 1.55; 95% confidence interval, 1.02-2.35; P = 0.039) in patients with advanced adenoma.

Conclusions: Lipid profiles are associated with recurrence of colorectal polyps. An elevated triglyceride level is an independent risk predictor of polyp recurrence in patients with advanced adenoma.

Keywords: Colorectal polyp; Lipid profile; Recurrence; Risk factor; Triglyceride.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Inclusion and exclusion criteria of the study participants
See this image and copyright information in PMC

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