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Comment
. 2020 Oct;586(7827):32-33.
doi: 10.1038/d41586-020-02565-1.

Modular synthesis enables molecular ju-jitsu in the fight against antibiotic resistance

Daniel J Blair, Martin D Burke
Comment

Modular synthesis enables molecular ju-jitsu in the fight against antibiotic resistance

Daniel J Blair et al. Nature. 2020 Oct.
No abstract available

Keywords: Drug discovery; Organic chemistry; Structural biology; Synthesis.

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  • Synthetic group A streptogramin antibiotics that overcome Vat resistance.
    Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT, van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray B, Jacobson MP, Mühle E, Chesneau O, Fraser JS, Seiple IB. Li Q, et al. Nature. 2020 Oct;586(7827):145-150. doi: 10.1038/s41586-020-2761-3. Epub 2020 Sep 23. Nature. 2020. PMID: 32968273 Free PMC article.

References

    1. Theuretzbacher, U., Outterson, K., Engel, A. & Karlén, A. Nature Rev. Microbiol. 18, 275–285 (2020). - PubMed - DOI
    1. Theuretzbacher, U. et al. Nature Rev. Microbiol. 18, 286–298 (2020). - PubMed - DOI
    1. Walsh, C. T. & Wencewicz, T. A. J. Antibiot. 67, 7–22 (2014). - PubMed - DOI
    1. Wright, P. M., Seiple, I. B. & Myers, A. G. Angew. Chem. Int. Edn 53, 8840–8869 (2014). - DOI
    1. Li, Q. et al. Nature 586, 145–150 (2020). - DOI

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