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. 2021 Mar;203(2):523-532.
doi: 10.1007/s00203-020-02042-3. Epub 2020 Sep 23.

Cytotoxicity and antimicrobial efficiency of selenium nanoparticles biosynthesized by Spirulina platensis

Heba S Abbas  1 , Doha H Abou Baker  2 , Entesar A Ahmed  3
Affiliations

Cytotoxicity and antimicrobial efficiency of selenium nanoparticles biosynthesized by Spirulina platensis

Heba S Abbas et al. Arch Microbiol. 2021 Mar.

Abstract

Nanotechnology has been exploited as a great scientific area especially in stating scenarios in drug discovery. In the present study, biosynthesized selenium nanoparticles (SeNPs) were prepared by the filtrate of Spirulina platensis after ultrasonication of their biomass. The biosynthesized SeNPs was characterized by using ultra-violet visible, Fourier transform infra-red spectroscopy, dynamic light scattering, and transmission electron microscope (TEM). The zeta potential of Biogenic SeNPs was -32.9 ± 8.12 mv that caused their stability. TEM micrographs elucidated the spherical shape of Biogenic SeNPs with a mean average size of 79.40 ± 44.26 nm. Biogenic SeNPs showed potential antimicrobial activity against gram-negative bacteria and yeast fungi C. albicans ATCC10231. No toxic effect was observed for SeNPs on normal kidney and liver cell lines. Biogenic SeNPs could be considered as a hopeful choice for future therapeutic applications because of their good biocompatibility and reactivity.

Keywords: Antimicrobial; Biogenic SeNPs; Cytotoxicity; Green nanotechnology; Spirulina platensis.

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References

    1. Abbas HS, Akilandeswari K, Muddukrishnaiah K (2020) The antifungal and antiovarian cancer properties of α-Fe2O3 and α- Fe2O3/Zno nanostructures synthesized by Spirulina platensis. IET nanobiotechnol. https://doi.org/10.1049/iet-nbt.2020.0055 - DOI - PubMed
    1. Abbas H, Abou Baker D (2019) Biological evaluation of selenium nanoparticles biosynthesized by Fusarium semitectum as antimicrobial and anticancer agents. Egy J Chem 63(4):1119–1133
    1. Abou Baker, D.H. 2020. Achillea millefolium L. ethyl acetate fraction induces apoptosis and cell cycle arrest in human cervical cancer (HeLa) cells. Annals of agriculture science. In press https://doi.org/10.1016/j.aoas.2020.03.003
    1. Abou Baker DH, Ibrahim BM, Hassan NS, Yousuf AF, El Gengaihi S (2020a) Exploiting Citrus aurantium seeds and their secondary metabolites in the management of Alzheimer disease. Toxicol Rep 7:723–729. https://doi.org/10.1016/j.toxrep.2020.06.001 - DOI - PubMed - PMC
    1. Abou Baker DH, Moghazy M, AlSayed AA (2020b) The in vitro cytotoxicity, antioxidant and antibacterial potential of Saturejahortensis L. essential oil cultivated in Egypt. Bioorg Chem. https://doi.org/10.1016/j.bioorg.2019.103559 - DOI - PubMed

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