Does laparoscopic reoperation yield symptomatic improvements similar to those of primary laparoscopic Heller myotomy in achalasia patients?
- PMID: 32968910
- DOI: 10.1007/s00464-020-07978-7
Does laparoscopic reoperation yield symptomatic improvements similar to those of primary laparoscopic Heller myotomy in achalasia patients?
Abstract
Background: Laparoscopic Heller myotomy fails in approximately 3.5% to 15% of patients. Evidence of successful laparoscopic reoperation is limited to a few studies.
Methods: This case-control study was conducted in patients who underwent laparoscopic Heller myotomy reoperation (LHM-R) from 2008 to 2016. The operative outcomes, preoperative and last follow-up manometric parameters, and symptom questionnaire results, including the Eckardt, Gastroesophageal Reflux Disease-Health Related Quality of Life (GERD-HRQL) and eating assessment tool (EAT-10) scores, were obtained. The data were compared with those of patients who underwent primary laparoscopic Heller myotomy (LHM-1).
Results: Thirty-five patients who underwent LHM-R and 35 patients who underwent LHM-1 were included. The reasons for failure in the LHM-R patient group included incomplete myotomy (71.4%), myotomy fibrosis (25.7%) and structural alterations in fundoplication (2.9%). The follow-up duration was 34 months for the LHM-R group and 24 months for the LHM-1 group (p = 0.557). The procedure was performed by laparoscopy in 100% of the patients in the two groups. No differences were found regarding surgical morbidity (11.4% LHM-R vs. 2.9% LHM-1, p = 0.164). The symptomatic outcomes were equivalent between groups (Eckardt p = 0.063, EAT-10 p = 0.166, GERD-HRQL p = 0.075). An IRP < 15 mmHg was achieved in 100% of the LHM-R and LHM-1 patients. At the last follow-up, 82.1% of the LHM-R patients and 91.4% of the LHM-1 patients were in symptomatic remission (p = 0.271).
Conclusion: The results achieved with LHM-R are similar to those achieved with LHM-1. Laparoscopic reoperation should be considered an effective and safe treatment after a failed Heller myotomy.
Keywords: Achalasia; Heller myotomy; Laparoscopy; Reoperation.
© 2020. Springer Science+Business Media, LLC, part of Springer Nature.
References
-
- Furuzawa-Carballeda J, Aguilar-León D, Gamboa-Domínguez A, Valdovinos MA, Nuñez-Álvarez C, Martín-del-Campo LA, Enríquez AB, Coss-Adame E, Svarch AE, Flores-Nájera A, Villa-Baños A, Ceballos JC, Torres-Villalobos G (2015) Achalasia—An autoimmune inflammatory disease: a cross-sectional study. J Immunol Res 2015:1–18. https://doi.org/10.1155/2015/729217 - DOI
-
- Furuzawa-Carballeda J, Torres-Landa S, Valdovinos MÁ, Coss-Adame E, Martín-del-Campo LA, Torres-Villalobos G (2016) New insights into the pathophysiology of achalasia and implications for future treatment. World J Gastroenterol 22:7892–7907. https://doi.org/10.3748/wjg.v22.i35.7892 - DOI - PubMed - PMC
-
- Furuzawa-Carballeda J, Zuñiga J, Hernández-Zaragoza DI, Barquera R, Marques-García E, Jiménez-Alvarez L, Cruz-Lagunas A, Ramírez G, Regino NE, Espinosa-Soto R, Yunis EJ, Romero-Hernández F, Azamar-Llamas D, Coss-Adame E, Valdovinos MA, Torres-Landa S, Palacios-Ramírez A, Breña B, Alejandro-Medrano E, Hernández-Ávila A, Granados J, Torres-Villalobos G (2018) An original Eurasian haplotype, HLA-DRB1*14:54-DQB1*05:03, influences the susceptibility to idiopathic achalasia. PLoS ONE 13:e0201676. https://doi.org/10.1371/journal.pone.0201676 - DOI - PubMed - PMC
-
- Verne GN, Hahn AB, Pineau BC, Hoffman BJ, Wojciechowski BW, Wu WC (1999) Association of HLA-DR and -DQ alleles with idiopathic achalasia. Gastroenterology 117:26–31 - DOI
-
- Williams VA, Peters JH (2009) Achalasia of the esophagus: a surgical disease. J Am Coll Surg 208:151–162. https://doi.org/10.1016/j.jamcollsurg.2008.08.027 - DOI - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
