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Case Reports
. 2021 Apr:42:264.e5-264.e8.
doi: 10.1016/j.ajem.2020.09.032. Epub 2020 Sep 16.

Mucormycosis with orbital compartment syndrome in a patient with COVID-19

Affiliations
Case Reports

Mucormycosis with orbital compartment syndrome in a patient with COVID-19

Amanda Werthman-Ehrenreich. Am J Emerg Med. 2021 Apr.

Abstract

During the current pandemic of COVID-19, a myriad of manifestations and complications has emerged and are being reported on. We are discovering patients with COVID-19 are at increased risk of acute cardiac injury, arrythmias, thromboembolic complications (pulmonary embolism and acute stroke), and secondary infection to name a few. I describe a novel case of COVID-19 in a previously healthy 33-year-old female who presented for altered mental status and proptosis. She was ultimately diagnosed with mucormycosis and orbital compartment syndrome, in addition to COVID-19. Early identification of these high morbidity conditions is key to allow for optimal treatment and improved outcomes.

Keywords: COVID-19; Mucormycosis; Orbital compartment syndrome.

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Conflict of interest statement

Declaration of Competing Interest None.

Figures

Fig. 1
Fig. 1
Chest x-ray: showing left lower pneumonia.
Fig. 2
Fig. 2
CT Head illustrating ethmoid sinus mucosal thickening.
Fig. 3
Fig. 3
MRI brain showing paranasal sinus mucosal disease.
Fig. 4
Fig. 4
MRI brain showing multifocal infarction.
Fig. 5
Fig. 5
Inpatient MRI showing developing fungal brain abscess.
Fig. 6
Fig. 6
Additional MRI image of fungal brain abscess.

References

    1. Cox G. 2020. Mucormycosis. Uptodate- July 2020.
    1. Serris A., Danion F., Lanternier F. Disease entities in mucormycosis. J Fungi. 2019;5(1):23. - PMC - PubMed
    1. Spellberg B., Edwards J., Ibrahim A. Novel perspectives on mucormycosis: pathophysiology, presentation, and management. Clin Microbiol Rev. 2005;18(3):556–569. - PMC - PubMed
    1. Jeong W., Keighley C., Wolfe R., et al. The epidemiology and clinical manifestations of mucormycosis: a systematic review and meta-analysis of case reports. Clin Microbiol Infect. 2019;25:26–34. - PubMed
    1. Chamilos G., Lewis R.E., Kontoyiannis D.P. Delaying amphotericin B-based frontline therapy significantly increases mortality among patients with hematologic malignancy who have zygomycosis. Clin Infect Dis. 2008;47:503–509. - PubMed

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