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Review
. 2021 May;259(5):1089-1101.
doi: 10.1007/s00417-020-04885-4. Epub 2020 Sep 25.

Markedly decreasing incidence of cause-specific blindness in Saxony (Eastern Germany)

Heiner Claessen  1   2   3 , Tatjana Kvitkina  4   5   6 , Maria Narres  4   5   6 , Christoph Trautner  7 , Bernd Bertram  8 , Andrea Icks  4   5   6
Affiliations
Review

Markedly decreasing incidence of cause-specific blindness in Saxony (Eastern Germany)

Heiner Claessen et al. Graefes Arch Clin Exp Ophthalmol. 2021 May.

Abstract

Purpose: To analyze the recent time trend in Saxony.

Methods: Data were based on administrative files in Saxony (Eastern Germany) to assess recipients of blindness allowance newly registered between January 1, 2009, and December 31, 2017. We estimated age-sex standardized incidence of all-cause and cause-specific blindness and used Poisson regression to examine age- and sex-adjusted time trends.

Results: We identified 5114 new cases of blindness (63.3% female, 59.9% ≥ 80 years). We observed a markedly decrease in incidence of blindness: all-causes 2009: 15.7 per 100,000 person years [95% confidence interval: 14.6-17.0]; 2017: 8.9 [8.1-9.8]; age-related macular degeneration 2009: 6.9 [6.1-7.7], 2017: 3.8 [3.3-4.3]; glaucoma 2009: 2.6 [2.2-3.1], 2017: 1.8 [1.4-2.2]; diabetic retinopathy 2009: 1.5 [1.2-1.9], 2017: 0.7 [0.5-1.0]; myopia 2009: 0.7 [0.5-1.1], 2017: 0.4 [0.2-0.5]; optic atrophy 2009: 0.9 [0.6-1.2], 2017: 0.5 [0.3-0.7]; and cataract 2009: 0.5 [0.3-0.8], 2017: 0.1 [0.1-0.3]. The annual reduction was between 5 (glaucoma, relative risk 0.95 [0.92-0.98]) and 16% (cataract, relative risk 0.84 [0.78-0.91]).

Conclusion: The age- and sex-standardized incidence of blindness decreased among all common causes of blindness in Saxony in the last decade.

Keywords: Blindness; Cause of blindness; Cause-specific blindness; Germany; Incidence; Time trend.

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