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. 2021 Jan;48(1):101-105.
doi: 10.1111/1346-8138.15626. Epub 2020 Sep 24.

Case of pemphigoid with immunoglobulin G antibodies to BP180 C-terminal domain and laminin-γ1 (p200) developed after pneumococcal vaccination

Nobuki Maki  1 , Takashi Hashimoto  2 , Tomoko Yamada  3 , Norito Ishii  4 , Daisuke Tsuruta  2 , Toshio Demitsu  5
Affiliations

Case of pemphigoid with immunoglobulin G antibodies to BP180 C-terminal domain and laminin-γ1 (p200) developed after pneumococcal vaccination

Nobuki Maki et al. J Dermatol. 2021 Jan.

Abstract

Pemphigoid cases have been reported in association with vaccination, including pneumococcal vaccination in infants but not in adults. There are also sporadic reports of pemphigoid diseases involving reactions to multiple autoantigens. We herein report a 75-year-old Japanese patient with pemphigoid who had immunoglobulin G antibodies to both the BP180 C-terminal domain and laminin-γ1 (p200), which developed 1 day after pneumococcal vaccination.

Keywords: BP180; laminin-γ1 (p200); pemphigoid disease; pneumococcal vaccination; trigger.

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References

    1. Venning VA, Wojnarowska F. Induced bullous pemphigoid. Clin Exp Dermatol 1995; 132(5): 831-832.
    1. Fournier B, Descamps V, Bouscarat F, Crickx B, Belaich S. Bullous pemphigoid induced by vaccination. Br J Dermatol 1996; 135(1): 153-154.
    1. Walmsley N, Hampton P. Bullous pemphigoid triggered by swine flu vaccination: case report and review of vaccine triggered pemphigoid. J Dermatol Case Rep 2011; 4: 74-76.
    1. Chacón GR, Sinha AA. Bullous pemphigoid after herpes zoster vaccine administration: association or coincidence? J Drugs Dermatol 2011; 10: 1328-1330.
    1. Sezin T, Egozi E, Hillou W, Avitan-Hersh E, Bergman R. Anti-laminin-332 mucous membrane pemphigoid developing after a diphtheria tetanus vaccination. JAMA Dermatol 2013; 149: 858-862.

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