doi: 10.1159/000132425.
Chromosome localization of the human renin gene (REN) by in situ hybridization
- PMID: 3297510
- DOI: 10.1159/000132425
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Chromosome localization of the human renin gene (REN) by in situ hybridization
Cytogenet Cell Genet.
1987.
Abstract
Previous studies by Southern blot analysis of human X mouse somatic cell hybrids localized the renin gene to region p21----qter of human chromosome 1. Using a DNA insert encoding exons 2-5, the renin gene was mapped to human chromosome bands 1q25----q32 by in situ hybridization. The sublocalization of the renin gene will facilitate subsequent detailed linkage analysis of human chromosome 1.
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