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. 2021 May-Jun;37(3S):S144-S148.
doi: 10.1097/IOP.0000000000001818.

Periphlebitis of the Superior Ophthalmic Vein

Jiyoung J Lee  1 , Liza M Cohen  2 , Christopher C Lo  2 , Daniel B Rootman  2
Affiliations

Periphlebitis of the Superior Ophthalmic Vein

Jiyoung J Lee et al. Ophthalmic Plast Reconstr Surg. 2021 May-Jun.

Abstract

Isolated orbital periphlebitis in the context of nonspecific orbital inflammation is rare. This case series describes 3 patients with periphlebitis of the superior ophthalmic vein, 2 of which were confirmed with pathology. All 3 cases had a history of Graves hyperthyroidism. Superior ophthalmic vein periphlebitis is a rare form of orbital inflammation presenting with proptosis and motility restriction yet few inflammatory signs. It may be associated with autoimmune hyperthyroidism and represent a rare feature of thyroid eye disease, or perhaps could be an overlap syndrome between thyroid eye disease and nonspecific orbital inflammation. Treatment response is variable and may require a prolonged course of steroids or other immunosuppressive medications.

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Conflict of interest statement

Proprietary Interest Statement: All authors report no conflicts of interest, financial, or otherwise. The authors alone are responsible for the content and writing of the paper.

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