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Comment
. 2020 Nov;10(11):1616.
doi: 10.1158/2159-8290.CD-NB2020-088. Epub 2020 Sep 25.

Context Determines Effects of TP53 Mutations

No authors listed
Comment

Context Determines Effects of TP53 Mutations

No authors listed. Cancer Discov. 2020 Nov.

Abstract

Mutations in TP53-the most commonly mutated gene in cancer-remain poorly understood. Recent work shows that the effects of mutations in this p53-encoding gene are dependent on context, including allelic state and the presence of microbial metabolites.

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