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Review
. 2021 Apr;34(3):134-144.
doi: 10.1089/vim.2020.0119. Epub 2020 Sep 23.

Coronavirus Disease 2019 Vaccine Development: An Overview

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Review

Coronavirus Disease 2019 Vaccine Development: An Overview

Riyadi Sumirtanurdin et al. Viral Immunol. 2021 Apr.

Abstract

To this day, the coronavirus disease 2019 (COVID-19) pandemic has not shown signs of abating. Moreover, the virus responsible for the pandemic, severe acute respiratory syndrome coronavirus 2, has evolved into three different variants. This phenomenon highlights an even greater need to develop drugs and vaccines to control the rate of infection and spread of the disease. As of July 7, 2020, at least 160 vaccine candidates, 21 of which have entered the clinical trial phase, have been developed. This article describes the latest advances in development, reliable platforms, strategies used, and challenges that remain in developing COVID-19 vaccines.

Keywords: SARS-CoV-2; challenges; platforms; progress.

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