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Case Reports
. 2020 Sep 29;20(1):716.
doi: 10.1186/s12879-020-05439-z.

A young adult with COVID-19 and multisystem inflammatory syndrome in children (MIS-C)-like illness: a case report

Aaron D Kofman  1 , Emma K Sizemore  2 , Joshua F Detelich  2 , Benjamin Albrecht  2 , Anne L Piantadosi  2
Affiliations
Case Reports

A young adult with COVID-19 and multisystem inflammatory syndrome in children (MIS-C)-like illness: a case report

Aaron D Kofman et al. BMC Infect Dis. .

Abstract

Background: A healthy 25-year-old woman developed COVID-19 disease with clinical characteristics resembling Multisystem Inflammatory Syndrome in Children (MIS-C), a rare form of COVID-19 described primarily in children under 21 years of age.

Case presentation: The patient presented with 1 week of weakness, dyspnea, and low-grade fevers, followed by mild cough, sore throat, vomiting, diarrhea, and lymph node swelling. She was otherwise healthy, with no prior medical history. Her hospital course was notable for profound acute kidney injury, leukocytosis, hypotension, and cardiac dysfunction requiring ICU admission and vasopressor support. MIS-C-like illness secondary to COVID-19 was suspected due to physical exam findings of conjunctivitis, mucositis, and shock. She improved following IVIG, aspirin, and supportive care, and was discharged on hospital day 5.

Conclusion: MIS-C-like illness should be considered in adults presenting with atypical clinical findings and concern for COVID-19. Further research is needed to support the role of IVIG and aspirin in this patient population.

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Conflict of interest statement

The authors declare that they have no competing interests.

References

    1. Kawasaki T. Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children. Japanese J Allergol. 1967;16:178. - PubMed
    1. Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet. 2020;395:1607. doi: 10.1016/S0140-6736(20)31094-1. - DOI - PMC - PubMed
    1. Verdoni L, Mazza A, Gervasoni A, Martelli L, Ruggeri M, Ciuffreda M, et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet. 2020;395:1771. doi: 10.1016/S0140-6736(20)31103-X. - DOI - PMC - PubMed
    1. Feldstein LR, Rose EB, Horwitz SM, Collins JP, Newhams MM, Son MBF, et al. Multisystem Inflammatory Syndrome in U.S. Children and Adolescents. N Engl J Med. 2020;383:334. doi: 10.1056/NEJMoa2021680. - DOI - PMC - PubMed
    1. Cha AE, Janes C. Young adults are also affected by Kawasaki-like disease linked coronavirus, doctors say. Washington Post. 2020.

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