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Case Reports
. 2020 Aug 20;6(10):1079-1081.
doi: 10.1016/j.jdcr.2020.08.019. eCollection 2020 Oct.

Successful treatment of refractory folliculitis decalvans with apremilast

Mirjam Fässler  1 , Susanne Radonjic-Hoesli  1 , Laurence Feldmeyer  1 , Valentina Imstepf  1 , Lorenzo Pelloni  1 , Nikhil Yawalkar  1 , Pierre A de Viragh  1
Affiliations
Case Reports

Successful treatment of refractory folliculitis decalvans with apremilast

Mirjam Fässler et al. JAAD Case Rep. .
No abstract available

Keywords: IL, interleukin.

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Figures

Fig 1
Fig 1
A, Oval patches of hair loss with erythema, follicular pustules, crusting, and hair tufts distributed along the scalp. B, Three weeks and 4 months after start of apremilast, with nearly complete regression of the inflammation.
Fig 2
Fig 2
A and B, Mostly superficial perifolliculitis with a mixed infiltrate composed of neutrophils, plasma cells, and eosinophils in a top-heavy pattern.
See this image and copyright information in PMC

References

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    1. Fernandez-Crehuet P., Vano-Galvan S., Molina-Ruiz A.M. Trichoscopic features of folliculitis decalvans: results in 58 patients. Int J Trichology. 2017;9:140–141. - PMC - PubMed
    1. Chiarini C., Torchia D., Bianchi B., Volpi W., Caproni M., Fabbri P. Immunopathogenesis of folliculitis decalvans: clues in early lesions. Am J Clin Pathol. 2008;130:526–534. - PubMed
    1. Harries M.J., Paus R. The pathogenesis of primary cicatricial alopecias. Am J Pathol. 2010;177:2152–2162. - PMC - PubMed
    1. Eyraud A., Milpied B., Thiolat D. Inflammasome activation characterizes lesional skin of folliculitis decalvans. Acta Derm Venereol. 2018;98:570–575. - PubMed

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