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Comment
. 2020 Oct 1;177(10):902-916.
doi: 10.1176/appi.ajp.2020.20081224.

A Brain-Centric Model of Suicidal Behavior

J John Mann  1 , Mina M Rizk  1
Affiliations
Comment

A Brain-Centric Model of Suicidal Behavior

J John Mann et al. Am J Psychiatry. .
No abstract available

Keywords: Stress-Diathesis Model; Suicide; Suicide Prevention.

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Figures

FIGURE 1.
FIGURE 1.. The stress-diathesis model of suicidal behaviora
a CBT=cognitive-behavioral therapy; BDNF=brain-derived neurotrophic factor; dACC=dorsal anterior cingulate cortex; DBT=dialectical behavioral therapy; dlPFC=dorsolateral prefrontal cortex; dmPFC=dorsomedial prefrontal cortex; DST=dexamethasone suppression test; GR=glucocorticoid receptor; HPA axis=hypothalamic-pituitary-adrenal axis; IFG=inferior frontal gyrus; mOFC=medial orbitofrontal cortex; MR=mineralocorticoid receptor; OFC=orbitofrontal cortex; rACC=rostral anterior cingulate cortex; rTMS=repetitive transcranial magnetic stimulation; SNRIs=serotonin-norepinephrine reuptake inhibitors; SSRIs=selective serotonin reuptake inhibitors; tDCS=transcranial direct current stimulation; TrkB=Tropomyosin-related kinase B; TSST=Trier Social Stress Test; vlPFC=ventrolateral prefrontal cortex; vmPFC=ventromedial prefrontal cortex.
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