Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jan;32(1-2):21-30.
doi: 10.1089/hum.2020.252. Epub 2020 Oct 30.

Bringing Gene Therapies for HIV Disease to Resource-Limited Parts of the World

Joseph M McCune  1 , Emily H Turner  1 , Adam Jiang  1 , Brian P Doehle  1
Affiliations

Bringing Gene Therapies for HIV Disease to Resource-Limited Parts of the World

Joseph M McCune et al. Hum Gene Ther. 2021 Jan.
No abstract available

PubMed Disclaimer

Conflict of interest statement

No competing financial interests exist.

Figures

Figure 1.
Figure 1.
The vision for the HIV Frontiers Program.
Figure 2.
Figure 2.
The key elements of the HIV Frontiers Program.
Figure 3.
Figure 3.
Critical considerations in the discovery, development, and clinical application of therapies targeting and editing long-lived cells in vivo.
See this image and copyright information in PMC

References

    1. United Nations Joint Programme on HIV/AIDS (UNAIDS). 2018. The youth bulge and HIV. https://www.unaids.org/sites/default/files/media_asset/the-youth-bulge-a.... (last accessed September 22, 2020).
    1. Hutter G, Nowak D, Mossner M, et al. . Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N Engl J Med 2009;360:692–698. - PubMed
    1. Gupta RK, Abdul-Jawad S, McCoy LE, et al. . HIV-1 remission following CCR5Delta32/Delta32 haematopoietic stem-cell transplantation. Nature 2019;568:244–248. - PMC - PubMed
    1. Collins DR, Gaiha GD, Walker BD. CD8(+) T cells in HIV control, cure and prevention. Nat Rev Immunol 2020;20:471–482. - PMC - PubMed
    1. Casado C, Galvez C, Pernas M, et al. . Permanent control of HIV-1 pathogenesis in exceptional elite controllers: a model of spontaneous cure. Sci Rep 2020;10:1902. - PMC - PubMed

Publication types

LinkOut - more resources