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Meta-Analysis
. 2020 Oct;24(4):235-243.
doi: 10.14744/AnatolJCardiol.2020.10406.

The patency of graft and anastomoses in sequential and individual coronary artery bypass grafting: A meta-analysis

Yongxing Li  1 , Baotang Liu  1 , Caifei Li  2 , YunChen Yu  1 , Xiaobo Liu  1 , Lei Li  1 , Zijun Li  1 , Chenxi Duan  1 , Sheng Luo  3 , Wenming Hou  1
Affiliations
Meta-Analysis

The patency of graft and anastomoses in sequential and individual coronary artery bypass grafting: A meta-analysis

Yongxing Li et al. Anatol J Cardiol. 2020 Oct.

Abstract

Objective:: To compare the patency of graft and anastomoses in sequential and individual coronary artery bypass grafting (CABG).

Methods:: Our study used the Cochrane Library database, Excerpta Medica database, Web of Science, and PubMed. Studies comparing the outcomes of graft or anastomosis patency were assessed independently by two reviewers to identify the literature of satisfaction. We used Review Manager and STATA software for statistical analysis.

Results:: Fifteen cohort studies were analyzed, including 10681 patients, 12957 grafts, and 4341 anastomoses, under sequential and individual CABG. Compared with the sequential group, the individual one is statistically significant in the graft patency [risk ratio (RR)=1.07, 95% confidence interval (CI ) 1.01–1.13; p=0.02] and anastomosis patency (RR=1.06, 95% CI 1.01–1.12; p=0.005).

Conclusion:: Our study suggested that the patency of the individual group, in terms of graft and anastomosis patency, is better than that of the sequential one.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
PRISMA flow chart of date selection
Figure 2
Figure 2
Forest plot of graft patency M-H - Mantel-Haenszel; CI - confidence interval
Figure 3
Figure 3
Forest plot for subgroup analysis of (a) follow-up rates >70%; (b) angiography to evaluate graft patency; (c) grafts by saphenous vein; and (d) surgery method by off-pump M-H - Mantel-Haenszel; CI - confidence interval
Figure 4
Figure 4
Forest plot of anastomosis patency M-H - Mantel-Haenszel; CI - confidence interval
Figure 5
Figure 5
Forest plot for subgroup analysis of (a) follow-up rates >70%; (b) angiography to evaluate anastomosis patency; (c) grafts by saphenous vein; and (d) surgery method by off-pump M-H - Mantel-Haenszel; CI - confidence interval
Figure 6
Figure 6
Sensitivity analysis of (a) graft patency and (b) anastomosis patency
See this image and copyright information in PMC

References

    1. Flemma RJ, Johnson WD, Lepley D Jr. Triple aorto-coronary vein bypass as treatment for coronary insufficiency. Arch Surg. 1971;103:82–3. - PubMed
    1. Walther S, Schuetz GM, Hamm B, Dewey M. Quality of reporting of systematic reviews and meta-analyses:PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) Rofo. 2011;183:1106–10. - PubMed
    1. Wells GA, Shea B, O'Connell Peterson J, Welch V, Losos M, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analysis. Ottawa (CA): Ottawa Hospital Research Institute; 2020. [cited 2020. May. 18] Available from: URL;http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp .
    1. Deeks JJ, Higgins JPT, Altman DG. Chapter 9:Analysing data and undertaking meta-analyses. In: Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011) The Cochrane Collaboration; 2011. Available from: URL;https://handbook-5-1.cochrane.org/
    1. Wendt D, Schmidt D, Wasserfuhr D, Osswald B, Thielmann M, Tossios P, et al. Comparison of sequential left internal thoracic artery grafting and separate left internal thoracic artery and venous grafting:A 5-year follow-up. Herz. 2010;35:397–402. - PubMed

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