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. 2020 Oct 1:371:m3377.
doi: 10.1136/bmj.m3377.

Risk of complicated birth at term in nulliparous and multiparous women using routinely collected maternity data in England: cohort study

Jennifer Jardine  1   2 , Andrea Blotkamp  2 , Ipek Gurol-Urganci  3   2 , Hannah Knight  3   2 , Tina Harris  4 , Jane Hawdon  5 , Jan van der Meulen  3   2 , Kate Walker  3 , Dharmintra Pasupathy  6
Affiliations

Risk of complicated birth at term in nulliparous and multiparous women using routinely collected maternity data in England: cohort study

Jennifer Jardine et al. BMJ. .

Abstract

Objectives: To determine the rate of complicated birth at term in women classified at low risk according to the National Institute for Health and Care Excellence guideline for intrapartum care (no pre-existing medical conditions, important obstetric history, or complications during pregnancy) and to assess if the risk classification can be improved by considering parity and the number of risk factors.

Design: Cohort study using linked electronic maternity records.

Participants: 276 766 women with a singleton birth at term after a trial of labour in 87 NHS hospital trusts in England between April 2015 and March 2016.

Main outcome measure: A composite outcome of complicated birth, defined as a birth with use of an instrument, caesarean delivery, anal sphincter injury, postpartum haemorrhage, or Apgar score of 7 or less at five minutes.

Results: Multiparous women without a history of caesarean section had the lowest rates of complicated birth, varying from 8.8% (4879 of 55 426 women, 95% confidence interval 8.6% to 9.0%) in those without specific risk factors to 21.8% (613 of 2811 women, 20.2% to 23.4%) in those with three or more. The rate of complicated birth was higher in nulliparous women, with corresponding rates varying from 43.4% (25 805 of 59 413 women, 43.0% to 43.8%) to 64.3% (364 of 566 women, 60.3% to 68.3%); and highest in multiparous women with previous caesarean section, with corresponding rates varying from 42.9% (3426 of 7993 women, 41.8% to 44.0%) to 66.3% (554 of 836 women, 63.0% to 69.5%).

Conclusions: Nulliparous women without risk factors have substantially higher rates of complicated birth than multiparous women without a previous caesarean section even if the latter have multiple risk factors. Grouping women first according to parity and previous mode of birth, and then within these groups according to presence of specific risk factors would provide greater and more informed choice to women, better targeting of interventions, and fewer transfers during labour than according to the presence of risk factors alone.

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Conflict of interest statement

Competing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare: all individuals are or have been partially or wholly funded by the Healthcare Quality Improvement Partnership for their contribution to the submitted work. DP is also funded by Tommy’s Charity. All authors also declare no financial relationships with any organisations that might have an interest in the submitted work in the previous three years. Dr Hawdon reports personal fees from expert medicolegal reporting, for defendant and claimant, on perinatal injury cases. The authors report no other relationships or activities that could appear to have influenced the submitted work.

Figures

Fig 1
Fig 1
Flowchart of cohort selection. NHS=national health service; HES=Hospital Episode Statistics
Fig 2
Fig 2
Association between number of types of risk factors and rates of complicated birth among women who gave birth at term after a trial of labour in England, 2015-16
See this image and copyright information in PMC

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