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. 2020 Oct 1;9(40):e00959-20.
doi: 10.1128/MRA.00959-20.

Whole-Genome Sequencing of Bacterial Isolates That Degrade the Cyanobacterial Toxin Microcystin-LR

Affiliations

Whole-Genome Sequencing of Bacterial Isolates That Degrade the Cyanobacterial Toxin Microcystin-LR

Alexander T McCartney et al. Microbiol Resour Announc. .

Abstract

We previously demonstrated that 13 bacterial isolates from Lake Erie, when grown in groups of four to five isolates per group, degraded the cyanobacterial toxin microcystin-LR (MC-LR) into nontoxic fragments. Whole-genome sequencing of these bacteria was performed to provide genus and species information and to predict putative MC-LR-degrading genes.

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References

    1. Schmale DG III, Ault AP, Saad W, Scott DT, Westrick JA. 2019. Perspectives on harmful algal blooms (HABs) and the cyberbiosecurity of freshwater systems. Front Bioeng Biotechnol 7:128. doi:10.3389/fbioe.2019.00128. - DOI - PMC - PubMed
    1. Bullerjahn GS, McKay RM, Davis TW, Baker DB, Boyer GL, D'Anglada LV, Doucette GJ, Ho JC, Irwin EG, Kling CL, Kudela RM, Kurmayer R, Michalak AM, Ortiz JD, Otten TG, Paerl HW, Qin B, Sohngen BL, Stumpf RP, Visser PM, Wilhelm SW. 2016. Global solutions to regional problems: collecting global expertise to address the problem of harmful cyanobacterial blooms. A Lake Erie case study. Harmful Algae 54:223–238. doi:10.1016/j.hal.2016.01.003. - DOI - PMC - PubMed
    1. Svircev Z, Drobac D, Tokodi N, Mijovic B, Codd GA, Meriluoto J. 2017. Toxicology of microcystins with reference to cases of human intoxications and epidemiological investigations of exposures to cyanobacteria and cyanotoxins. Arch Toxicol 91:621–650. doi:10.1007/s00204-016-1921-6. - DOI - PubMed
    1. Welker M, Steinberg C. 2000. Rates of humic substance photosensitized degradation of microcystin-LR in natural waters. Environ Sci Technol 34:3415–3419. doi:10.1021/es991274t. - DOI
    1. Rastogi RP, Sinha RP, Incharoensakdi A. 2014. The cyanotoxin-microcystins: current overview. Rev Environ Sci Biotechnol 13:215–249. doi:10.1007/s11157-014-9334-6. - DOI

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