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Case Reports
. 2020 Aug 8;6(10):1113-1115.
doi: 10.1016/j.jdcr.2020.07.054. eCollection 2020 Oct.

Generalized granuloma annulare: A widespread response to limited application of compounded 2% topical tofacitinib

Joseph S Durgin  1 , Bridget E Shields  1 , Misha Rosenbach  1
Affiliations
Case Reports

Generalized granuloma annulare: A widespread response to limited application of compounded 2% topical tofacitinib

Joseph S Durgin et al. JAAD Case Rep. .
No abstract available

Keywords: IL, interleukin; JAK, Janus kinase.

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Figures

Fig 1
Fig 1
Generalized granuloma annulare before and after topical 2% tofacitinib ointment applied to right arm. A and B, Annular, red to violaceous plaques on the trunk and forearm. C and D, Improvement in lesions on upper and lower right arm after 12 weeks of topical tofacitinib.
See this image and copyright information in PMC

References

    1. Thornsberry L.A., English J.C. Etiology, diagnosis, and therapeutic management of granuloma annulare: an update. Am J Clin Dermatol. 2013;14(4):279–290. - PubMed
    1. Piette E.W., Rosenbach M. Granuloma annulare: pathogenesis, disease associations and triggers, and therapeutic options. J Am Acad Dermatol. 2016;75(3):467–479. - PubMed
    1. Rosenbach M. Janus kinase inhibitors offer promise for a new era of targeted treatment for granulomatous disorders. J Am Acad Dermatol. 2020;82(3):e91–e92. - PubMed
    1. Damsky W., King B.A. Treatment of granuloma annulare with tofacitinib 2% ointment. JAAD Case Rep. 2020;6(1):69–71. - PMC - PubMed
    1. Wang J., Khachemoune A. Granuloma annulare: a focused review of therapeutic options. Am J Clin Dermatol. 2018;19(3):333–344. - PubMed

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