Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Jun 8;4(5):480-484.
doi: 10.1002/ags3.12354. eCollection 2020 Sep.

Precautions for avoiding pulmonary morbidity after esophagectomy

Affiliations
Review

Precautions for avoiding pulmonary morbidity after esophagectomy

Naoya Yoshida et al. Ann Gastroenterol Surg. .

Abstract

Pulmonary morbidity is the most common complication after esophagectomy. Importantly, it is the main cause of surgery-related mortality and possibly adversely affects the long-term outcome after surgery in patients with esophageal cancer. There is considerable accumulated evidence on multidisciplinary approaches to reduce post-operative pulmonary morbidity. A comprehensive review of the precautionary measures that have so far been shown to be effective in previous literature is of utmost importance. We herein update and summarize the perioperative and surgical approaches to diminish pulmonary morbidity. Pre-operative smoking cessation, respiratory rehabilitation, maintaining oral hygiene, perioperative nutritional intervention, enforcement of less invasive surgery, perioperative administration of steroid, and total management by a multidisciplinary team could be the key factors contributing to reduction in pulmonary morbidity.

Keywords: esophageal cancer; precaution; pulmonary complication; surgery.

PubMed Disclaimer

Conflict of interest statement

Drs. Naoya Yoshida belongs to the department supported by Chugai Pharmaceutical Co., Ltd and Yakuruto Honsya Co., Ltd, but has no conflicts of interest regarding this research. Dr Yoshifumi Baba belongs to the department supported by Ono Pharmaceutical Co., Ltd, but has no conflicts of interest regarding this research. Hideo Baba and the other co‐authors (KH and MI) have no conflicts of interests or financial ties to disclose.

Figures

Figure 1
Figure 1
Summary of precautions for avoiding pulmonary morbidity after esophagectomy. MIE, minimally invasive esophagectomy

References

    1. Takeuchi H, Miyata H, Gotoh M, Kitagawa Y, Baba H, Kimura W, et al. A risk model for esophagectomy using data of 5354 patients included in a Japanese nationwide web‐based database. Ann Surg. 2014;260:259–66. - PubMed
    1. Yoshida N, Yamamoto H, Baba H, Miyata H, Watanabe M, Toh Y, et al. Can minimally invasive esophagectomy replace open esophagectomy for esophageal cancer?: latest analysis of 24,233 esophagectomies from the Japanese national clinical database. Ann Surg. 2020. 10.1097/SLA.0000000000003222. Epub ahead of print. - DOI - PubMed
    1. Yang CK, Teng A, Lee DY, Rose K. Pulmonary complications after major abdominal surgery: National Surgical Quality Improvement Program analysis. J Surg Res. 2015;198:441–9. - PubMed
    1. Yoshida N, Morito A, Nagai Y, Baba Y, Miyamoto Y, Iwagami S, et al. Clinical Importance of sputum in the respiratory tract as a predictive marker of postoperative morbidity after esophagectomy for esophageal cancer. Ann Surg Oncol. 2019;26:2580–6. - PubMed
    1. Molena D, Mungo B, Stem M, Lidor AO. Incidence and risk factors for respiratory complications in patients undergoing esophagectomy for malignancy: a NSQIP analysis. Semin Thorac Cardiovasc Surg. 2014;26:287–94. - PubMed