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Multicenter Study
. 2021 Oct;62(1):171-176.
doi: 10.1007/s10840-020-00886-9. Epub 2020 Oct 1.

Creating a safe workplace by universal testing of SARS-CoV-2 infection in asymptomatic patients and healthcare workers in the electrophysiology units: a multi-center experience

Sanghamitra Mohanty  1 , Dhanunjaya Lakkireddy  2 , Chintan Trivedi  1 , Bryan MacDonald  1 , Angel Quintero Mayedo  1 , Domenico G Della Rocca  1 , Donita Atkins  2 , Peter Park  2 , Alap Shah  2 , Rakesh Gopinathannair  2 , Amin Al-Ahmad  1 , John D Burkhardt  1 , G J Gallinghouse  1 , Mohamed Bassiouny  1 , Luigi Di Biase  1   3 , David Kessler  1   4 , David Tschopp  1   4 , Paul Coffeen  1   4 , Rodney Horton  1 , Robert Canby  1 , Andrea Natale  5   6   7
Affiliations
Multicenter Study

Creating a safe workplace by universal testing of SARS-CoV-2 infection in asymptomatic patients and healthcare workers in the electrophysiology units: a multi-center experience

Sanghamitra Mohanty et al. J Interv Card Electrophysiol. 2021 Oct.

Abstract

Background: As the coronavirus cases continue to surge, the urgent need for universal testing to identify positive cases for effective containment of this highly contagious pandemic has become the center of attention worldwide. However, in spite of extensive discussions, very few places have even attempted to implement it. We evaluated the efficacy of widespread testing in creating a safe workplace in our electrophysiology (EP) community. Furthermore, we assessed the new infection rate in patients undergoing EP procedure, to see if identification and exclusion of positive cases facilitated establishment of a risk-free operating environment.

Methods: Viral-RNA and serology tests were conducted in 1670 asymptomatic subjects including patients and their caregivers and staff in our EP units along with the Emergency Medical Service (EMS) staff.

Results: Of 1670, 758 (45.4%) were patients and the remaining 912 were caregivers, EMS staff, and staff from EP clinic and lab. Viral-RNA test revealed 64 (3.8%) positives in the population. A significant increase in positivity rate was observed from April to June 2020 (p = 0.02). Procedures of positive cases (n = 31) were postponed until they tested negative at retesting. Staff testing positive (n = 33) were retested before going back to work after 2 weeks. Because of suspected exposure, 67 staff were retested and source was traced. No new infections were reported in patients during or within 2 weeks after the hospital-stay.

Conclusions: Universal testing to identify positive cases was helpful in creating and maintaining a safe working environment without exposing patients and staff to new infections in the EP units.

Trial registration: Trial Registration Number: clinicaltrials.gov : NCT04352764.

Keywords: Asymptomatic; COVID-19; Electrophysiology; Serology; Universal testing; Viral-RNA.

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Conflict of interest statement

Natale A: consulting fees/honoraria: Abbott Medical, Boston Scientific, Medtronic, Biotronik, Biosense Webster, Baylis

Di Biase L: consultant/Advisory Board; Biosense Webster, Hansen Medical

J.D. Burkhardt: Biosense Webster, Boehringer Ingelheim, Stereotaxis

R. Horton: Biosense Webster, St. Jude Medical, Toray, Boston Scientific & Hansen.

D.Lakkireddy: consultant/speaker—Abbott, Medtronic, Boston Scientific, Biotronik, Biosense Webster, North East Scientific, Alta-Thera, Janssen

R. Gopinathannair: Abbott/ Biotronik

Figures

Fig. 1
Fig. 1
Work-flow of the study with testing and care continuum
Fig. 2
Fig. 2
Bar diagram showing distribution of viral-RNA positive cases among the asymptomatic patient population. A total of 64 (3.8%) cases were positive for viral RNA at baseline. They included 31 (4.09%) patients, 26 (5.5%) EP staff, 2 (0.9%) caregivers, and 5 (2.28%) EMS staff
Fig. 3
Fig. 3
Graph showing increase in the rate of positive cases among asymptomatic individuals from April to June 2020. The positive rate was 2.79% (21/753) in the month of April, 3.81% (13/341) in May, and 5.2% (30/576) in June (p = 0.01)
See this image and copyright information in PMC

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