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. 2020 Sep 30;12(10):1113.
doi: 10.3390/v12101113.

Wild Boar as a Sylvatic Reservoir of Hepatitis E Virus in Poland: A Cross-Sectional Population Study

Iwona Kozyra  1 , Artur Jabłoński  2 , Ewelina Bigoraj  1 , Artur Rzeżutka  1
Affiliations

Wild Boar as a Sylvatic Reservoir of Hepatitis E Virus in Poland: A Cross-Sectional Population Study

Iwona Kozyra et al. Viruses. .

Abstract

The most important wildlife species in the epidemiology of hepatitis E virus (HEV) infections are wild boars, which are also the main reservoir of the virus in a sylvatic environment. The aim of the study was a serological and molecular assessment of the prevalence of HEV infections in wild boars in Poland. In total, 470 pairs of samples (wild boar blood and livers) and 433 samples of faeces were tested. An ELISA (ID.vet, France) was used for serological analysis. For the detection of HEV RNA, real-time (RT)-qPCR was employed. The presence of specific anti-HEV IgG antibodies was found in 232 (49.4%; 95%CI: 44.7-54%) sera, with regional differences observed in the seroprevalence of infections. HEV RNA was detected in 57 (12.1%, 95%CI: 9.3-15.4%) livers and in 27 (6.2%, 95%CI: 4.1-8.9%) faecal samples, with the viral load ranging from 1.4 to 1.7 × 1011 G.C./g and 38 to 9.3 × 107 G.C./mL, respectively. A correlation between serological and molecular results of testing of wild boars infected with HEV was shown. HEV infections in wild boars appeared to be common in Poland.

Keywords: hepatitis E virus; infection prevalence; serosurvey; wild boar.

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Smith D.B., Izopet J., Nicot F., Simmonds P., Jameel S., Meng X.-J., Norder H., Okamoto H., Van Der Poel W.H., Reuter G., et al. Update: Proposed reference sequences for subtypes of hepatitis E virus (species Orthohepevirus A) J. Gen. Virol. 2020;101:692–698. doi: 10.1099/jgv.0.001435. - DOI - PMC - PubMed
    1. Tei S., Kitajima N., Takahashi K., Mishiro S. Zoonotic transmission of hepatitis E virus from deer to human beings. Lancet. 2003;362:371–373. doi: 10.1016/S0140-6736(03)14025-1. - DOI - PubMed
    1. Takahashi K., Kitajima N., Abe N., Mishiro S. Complete or near-complete nucleotide sequences of hepatitis E virus genome recovered from a wild boar, a deer, and four patients who ate the deer. Virology. 2004;330:501–505. doi: 10.1016/j.virol.2004.10.006. - DOI - PubMed
    1. Li T.-C., Chijiwa K., Sera N., Ishibashi T., Etoh Y., Shinohara Y., Kurata Y., Ishida M., Sakamoto S., Takeda N., et al. Hepatitis E virus transmission from wild boar meat. Emerg. Infect. Dis. 2005;11:1958–1960. doi: 10.3201/eid1112.051041. - DOI - PMC - PubMed
    1. Rivero-Juárez A., Frías M., Martinez-Peinado A., Risalde M.A., Rodriguez-Cano D., Camacho A., García-Bocanegra I., Cuenca-Lopez F., Gómez-Villamandos J.C., Rivero A. Familial hepatitis E outbreak linked to wild boar meat consumption. Zoonoses Public Health. 2017;64:561–565. doi: 10.1111/zph.12343. - DOI - PubMed

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