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. 2020 Oct 2;20(1):948.
doi: 10.1186/s12885-020-07389-w.

The psychosocial determinants of quality of life in breast cancer survivors: a scoping review

Michael G Culbertson  1 , Kathleen Bennett  1 , Catherine M Kelly  2 , Linda Sharp  3 , Caitriona Cahir  4
Affiliations

The psychosocial determinants of quality of life in breast cancer survivors: a scoping review

Michael G Culbertson et al. BMC Cancer. .

Abstract

Background: Breast cancer care today involves state-of-the-art biomedical treatment but can fail to address the broader psychosocial and quality-of-life (QoL) issues associated with the transition to breast cancer survivorship. This scoping review examines the evidence on the influence of psychosocial determinants on QoL in breast cancer survivors.

Methods: Scoping review methodology was used to: (1) identify the research question(s); (2) identify relevant studies; (3) undertake study selection; (4) extract data; (5) collate, summarise and report the results.

Results: A total of 33 studies met the inclusion criteria. The majority of studies were conducted in the US (n = 22, 67%) and were mainly cross-sectional (n = 26, 79%). Sixteen psychosocial determinants of QoL were identified. Social support (n = 14, 42%), depression (n = 7, 21%) and future appraisal and perspective (n = 7, 21%) were the most frequently investigated determinants. Twelve different QoL measures were used. A range of different measurement tools were also used per psychosocial determinant (weighted average = 6). The 14 studies that measured the influence of social support on QoL employed 10 different measures of social support and 7 different measures of QoL. In general, across all 33 studies, a higher level of a positive influence and a lower level of a negative influence of a psychosocial determinant was associated with a better QoL e.g. higher social support and lower levels of depression were associated with a higher/better QoL. For some determinants such as spirituality and coping skills the influence on QoL varied, but these determinants were less commonly investigated.

Conclusion: Consensus around measures of QoL and psychological determinants would be valuable and would enable research to determine the influence of psychosocial determinants on QoL adequately. Research in other healthcare settings beyond the US is required, in order to understand the influence of organisation and follow-up clinical and supportive care on psychosocial determinants and QoL and to improve the quality of care in breast cancer survivors.

Keywords: Breast cancer; Psychosocial; Quality of life; Scoping review; Survivorship.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
PRISMA diagram of selection of studies
See this image and copyright information in PMC

References

    1. Allemani C, Matsuda T, Di Carlo V, Harewood R, Matz M, Niksic M, et al. Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries. Lancet. 2018;391(10125):1023–1075. doi: 10.1016/S0140-6736(17)33326-3. - DOI - PMC - PubMed
    1. Sharp L, Deady S, Gallagher P, Molcho M, Pearce A, Alforque Thomas A, et al. The magnitude and characteristics of the population of cancer survivors: using population-based estimates of cancer prevalence to inform service planning for survivorship care. BMC Cancer. 2014;14(1):767. doi: 10.1186/1471-2407-14-767. - DOI - PMC - PubMed
    1. WHO. Cancer incidence and mortality statistics worldwide and by region http://gco.iarc.fr/today/data/factsheets/cancers/20-Breast-fact-sheet.pdf: The Global Cancer Observatory. 2018.
    1. Bell K, Ristovski-Slijepcevic S. Cancer survivorship: why labels matter. J Clin Oncol. 2013;31(4):409–411. doi: 10.1200/JCO.2012.43.5891. - DOI - PubMed
    1. Denlinger CS, Carlson RW, Are M, Baker KS, Davis E, Edge SB, et al. Survivorship: introduction and definition. Clinical practice guidelines in oncology. J Natl Compr Cancer Netw. 2014;12(1):34–45. doi: 10.6004/jnccn.2014.0005. - DOI - PMC - PubMed

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