The changing face of gastric cancer: epidemiologic trends and advances in novel therapies
- PMID: 33009508
- DOI: 10.1038/s41417-020-00234-z
The changing face of gastric cancer: epidemiologic trends and advances in novel therapies
Abstract
Gastric cancer is an aggressive solid-tumor malignancy with poor prognosis. The epidemiologic face of gastric cancer is changing and further insight into its heterogenous immunohistopathologic nature is needed to develop personalized therapies for specific patient populations. In this review, we highlight changes in gastric cancer epidemiology with a special emphasis on racial and ethnic variations and discuss the implications of current clinical and preclinical treatment advances.
Similar articles
-
Gastric Cancer: Recent Molecular Classification Advances, Racial Disparity, and Management Implications.J Oncol Pract. 2018 Apr;14(4):217-224. doi: 10.1200/JOP.17.00025. J Oncol Pract. 2018. PMID: 29641950 Review.
-
Advances of Molecular Targeted Therapy in Gastric Cancer.J Gastrointest Cancer. 2016 Jun;47(2):125-34. doi: 10.1007/s12029-016-9806-8. J Gastrointest Cancer. 2016. PMID: 26875080 Review.
-
Targeted therapy for gastric cancer: molecular pathways and ongoing investigations.Biochim Biophys Acta. 2014 Aug;1846(1):232-7. doi: 10.1016/j.bbcan.2014.05.003. Epub 2014 May 22. Biochim Biophys Acta. 2014. PMID: 24858418 Review.
-
Gastric cancer: a primer on the epidemiology and biology of the disease and an overview of the medical management of advanced disease.J Natl Compr Canc Netw. 2010 Apr;8(4):437-47. doi: 10.6004/jnccn.2010.0033. J Natl Compr Canc Netw. 2010. PMID: 20410336 Review.
-
Translating gastric cancer genomics into targeted therapies.Crit Rev Oncol Hematol. 2016 Apr;100:141-6. doi: 10.1016/j.critrevonc.2016.02.007. Epub 2016 Feb 18. Crit Rev Oncol Hematol. 2016. PMID: 26947813 Review.
Cited by
-
Machine learning-based identification of a novel prognosis-related long noncoding RNA signature for gastric cancer.Front Cell Dev Biol. 2022 Nov 11;10:1017767. doi: 10.3389/fcell.2022.1017767. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36438557 Free PMC article.
-
Lenvatinib inhibits the growth of gastric cancer patient-derived xenografts generated from a heterogeneous population.J Transl Med. 2022 Mar 7;20(1):116. doi: 10.1186/s12967-022-03317-7. J Transl Med. 2022. PMID: 35255940 Free PMC article.
-
Autoimmunity as an Etiological Factor of Cancer: The Transformative Potential of Chronic Type 2 Inflammation.Front Cell Dev Biol. 2021 Jun 21;9:664305. doi: 10.3389/fcell.2021.664305. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34235145 Free PMC article. Review.
-
The use of indocyanine green and near-infrared fluorescence in the detection of metastatic lymph nodes during oesophageal and gastric cancer resection: a systematic review and meta-analysis.Surg Endosc. 2025 Jun;39(6):3525-3538. doi: 10.1007/s00464-025-11703-7. Epub 2025 Apr 18. Surg Endosc. 2025. PMID: 40251309 Free PMC article.
-
Immune Score Predicts Outcomes of Gastric Cancer Patients Treated with Adjuvant Chemoradiotherapy.J Oncol. 2021 Dec 27;2021:9344124. doi: 10.1155/2021/9344124. eCollection 2021. J Oncol. 2021. PMID: 34987582 Free PMC article.
References
-
- Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424. - DOI
-
- North American Association of Central Cancer Registries. NAACCR Fast Stats: an interactive tool for quick access to key NAACCR cancer statistics. 2019. https://faststats.naaccr.org/selections.php?#Output .
-
- Surveillance E, End Results Program. Cancer Stat Facts: Stomach Cancer. 2019. https://seer.cancer.gov/statfacts/html/stomach.html .
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical