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Comment
. 2021 Jan 4;223(1):175-178.
doi: 10.1093/infdis/jiaa630.

Minor Allele of Interferon-Induced Transmembrane Protein 3 Polymorphism (rs12252) Is Covered Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Mortality: A Worldwide Epidemiological Investigation

Abhijit Pati  1 , Sunali Padhi  1 , Subham Suvankar  1 , Aditya K Panda  1
Affiliations
Comment

Minor Allele of Interferon-Induced Transmembrane Protein 3 Polymorphism (rs12252) Is Covered Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Mortality: A Worldwide Epidemiological Investigation

Abhijit Pati et al. J Infect Dis. .
No abstract available

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References

    1. Zhang Y, Qin L, Zhao Y, et al. Interferon-induced transmembrane protein 3 genetic variant rs12252-C associated with disease severity in coronavirus disease 2019. J Infect Dis 2020; 222:34–7. - PMC - PubMed
    1. Nikoloudis D, Kountouras D, Hiona A. The frequency of combined IFITM3 haplotype involving the reference alleles of both rs12252 and rs34481144 is in line with COVID-19 standardized mortality ratio of ethnic groups in England. Europe PMC [Preprint, not peer-reviewed]. Posted online 15 May 2020. doi:10.20944/preprints202005.0273.v1. - PMC - PubMed
    1. Martins JSC, Oliveira MLA, Garcia CC, Siqueira MM, Matos AR. Investigation of human IFITM3 polymorphisms rs34481144A and rs12252C and risk for influenza A(H1N1)pdm09 severity in a Brazilian cohort. Front Cell Infect Microbiol 2020; 10:352. - PMC - PubMed
    1. Makvandi-Nejad S, Laurenson-Schafer H, Wang L, et al. Lack of truncated IFITM3 transcripts in cells homozygous for the rs12252-C variant that is associated with severe influenza infection. J Infect Dis 2018; 217:257–62. - PubMed
    1. Randolph AG, Yip WK, Allen EK, et al. ; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators Evaluation of IFITM3 rs12252 association with severe pediatric influenza infection. J Infect Dis 2017; 216:14–21. - PMC - PubMed