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. 2021 Mar;75(3):e13748.
doi: 10.1111/ijcp.13748. Epub 2020 Oct 27.

Vitamin D and COVID-19: It is time to act

Andrius Bleizgys  1
Affiliations

Vitamin D and COVID-19: It is time to act

Andrius Bleizgys. Int J Clin Pract. 2021 Mar.

Abstract

Vitamin D (VitD) deficiency is considered a global problem and might be associated with increased susceptibility to COVID-19 illness. In the light of COVID-19 pandemic, VitD might be a promising agent for fighting the SARS-CoV-2, since VitD is involved in various pathophysiological mechanisms that occur during COVID-19 infection. High-dose VitD supplementation, particularly for risk groups, could be recommended to achieve and maintain optimal (range 40-60 ng/mL) serum 25-hydroxy vitamin D levels (marker of VitD status) both for COVID-19 prevention and treatment.

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Conflict of interest statement

The author declares no conflict of interest.

References

    1. Kakodkar P, Kaka N, Baig MN. A comprehensive literature review on the clinical presentation, and management of the pandemic coronavirus disease 2019 (COVID‐19). Cureus. 2020;12:e7560. - PMC - PubMed
    1. Misra DP, Agarwal V, Gasparyan AY, Zimba O. Rheumatologists' perspective on coronavirus disease 19 (COVID‐19) and potential therapeutic targets. Clin Rheumatol. 2020;39:2055‐2062. - PMC - PubMed
    1. Zabetakis I, Lordan R, Norton C, Tsoupras A. COVID‐19: the inflammation link and the role of nutrition in potential mitigation. Nutrients. 2020;12:1466. - PMC - PubMed
    1. Grant WB, Lahore H, McDonnell SL, et al. Evidence that vitamin D supplementation could reduce risk of influenza and COVID‐19 infections and deaths. Nutrients. 2020;12:988. - PMC - PubMed
    1. de Lucena TMC, da Silva Santos AF, de Lima BR, de Albuquerque Borborema ME, de Azevedo SJ. Mechanism of inflammatory response in associated comorbidities in COVID‐19. Diabetes Metab Syndr. 2020;14:597‐600. - PMC - PubMed