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Case Reports
. 2020 Aug 7:36:256.
doi: 10.11604/pamj.2020.36.256.23129. eCollection 2020.

Idiopathic focal organizing pneumonia mimicking malignancy

Emrah Dogan  1 , Utku Tapan  2 , Ozge Oral Tapan  2 , Turhan Togan  3 , Özgür Ilhan Çelik  4
Affiliations
Case Reports

Idiopathic focal organizing pneumonia mimicking malignancy

Emrah Dogan et al. Pan Afr Med J. .

Abstract

Idiopathic FOP is a rare type of COP. What we know on this subject is made up of a few clinical cases published in recent years. Our patient was admitted to the hospital with an intermittent coughing complaint that worsens over time. Due to a suspicion of malignancy, a radiological evaluation was requested including a PET-CT and a transbronchial biopsy was performed. Until the last part of our algorithm, the patient profile was clinically and radiologically in favor of the diagnosis of malignancy but, in the end, the diagnosis of FOP was fixed with a follow-up decision. In conclusion, FOP is a relatively new entity that should be kept in mind in the differential diagnosis of malignancy.

Keywords: Idiopathic focal organizing pneumonia; cryptogenic organizing pneumonia; mimicking malignity.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
an irregular density was observed in the lower segment of the right lung on the chest X-ray (A), solid mass with speculated irregular contours mimicking malignancy, in the posterior basal segment of the lower lobe of the right lung (B)
Figure 2
Figure 2
low grade FDG uptake in PET-CT (SUV: 1, 8)
Figure 3
Figure 3
comparison of images taken by PET-CT and CT
Figure 4
Figure 4
moderate inflammation appearance in the wall of the bronchi under the light microscope
Figure 5
Figure 5
patchy involvement with loose fibroblastic plugs in the second biopsy
Figure 6
Figure 6
significant regression in control X-ray graphy and CT images
See this image and copyright information in PMC

References

    1. Kilaru H, Jalna MV, Kilaru SC, Nandury EC, Khan Focal organizing pneumonia simulating lung malignancy: treated with prednisolone. M.Respirol Case Rep. 2019 Aug 5;7(7):e00469. - PMC - PubMed
    1. Huo Z, Feng R, Tian X, Zhang H, Huo L, Liu H. Clinicopathological findings of focal organizing pneumonia: a retrospective study of 37 cases. Int J Clin Exp Pathol. 2015 Jan 1;8(1):511–516. - PMC - PubMed
    1. Niksarlioglu EY, Ozkan GZ, Bakan ND, Yurt S, Kilic L, Camsari G. Cryptogenic organizing pneumonia: clinical and radiological features, treatment outcomes of 17 patients, and review of the literature. Turk J Med Sci. 2016 Dec 20;46(6):1712–1718. - PubMed
    1. Cordier JF. Update on cryptogenic organising pneumonia (Idiopathic bronchiolitis obliterans organising pneumonia. Swiss Med Wkly. 2002 Nov 23;132(41-42):588–91. - PubMed
    1. Wells AU. Cryptogenic organising pneumonia. Seminars in Respiratory and Critical Care Med. 2001 Aug;22(4):449–60. - PubMed

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