Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Aug 18:10:1339.
doi: 10.3389/fonc.2020.01339. eCollection 2020.

Selection and Outcomes in Abdominoperineal Resection

Affiliations
Review

Selection and Outcomes in Abdominoperineal Resection

Norbert Garcia-Henriquez et al. Front Oncol. .

Abstract

Since the initial descriptions of the abdominoperineal resection by Sir William Ernest Miles which was then followed by the perfection of the total mesorectal excision by Professor Bill Heald, the surgical management of rectal cancer has made tremendous strides. However, even with the advent and sophistication of neoadjuvant therapy, there remains a formidable amount of patients requiring an abdominoperineal resection. The purpose of this review is to delineate the indication and selection process by which patients are determined to require an abdominoperineal resection, as well as the oncologic and overall outcomes associated with the operation.

Keywords: extralevator abdominoeperineal excision (ELAPE); extrasphincteric APR; indication; intersphincteric APR; outcomes; selection.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Plane of perineal dissection for APR. (A) Intersphincteric dissection; (B) Extrasphincteric dissection (standard APR); (C) Extralevator abdominoperineal excision (ELAPE).
Figure 2
Figure 2
Complete ELAPE specimen.
Figure 3
Figure 3
Perineal wound closure following ELAPE.

References

    1. Campos FG, Habr-Gama A, Nahas SC, Perez RO. Abdominoperineal excision: evolution of a centenary operation. Dis Colon Rectum. (2012) 55:844–53. 10.1097/DCR.0b013e31825ab0f7 - DOI - PubMed
    1. Hawkins AT, Albutt K, Wise PE, Alavi K, Sudan R, Kaiser AM, et al. . Abdominoperineal resection for rectal cancer in the twenty-first century: indications, techniques, and outcomes. J Gastrointest Surg. (2018) 22:1477–87. 10.1007/s11605-018-3750-9 - DOI - PubMed
    1. Miles WE. A method of performing abdomino-perineal excision for carcinoma of the rectum and of the terminal portion of the pelvic colon. Lancet. (1908) 2:1812–3. 10.1016/S0140-67360099076-7 - DOI - PubMed
    1. Miles WE. The radical abdomino-perineal operation for cancer of the pelvic colon. BMJ. (1910) 11:941–3. - PubMed
    1. Schmitz RL, Nelson PA, Martin GB, Boghossian HM. Synchronous (two-team) abdominoperineal resection of the rectum. AMA Arch Surg. (1958) 77:492–7. 10.1001/archsurg.1958.04370010024003 - DOI - PubMed