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Case Reports
. 2020 Sep;32(112):327-331.
doi: 10.22038/ijorl.2020.42693.2394.

Metastasis of Colon Adenocarcinoma to Maxillary Gingiva and Palate

Zohreh Dalirsani  1 , Nooshin Mohtasham  2 , Negin Samiee  3
Affiliations
Case Reports

Metastasis of Colon Adenocarcinoma to Maxillary Gingiva and Palate

Zohreh Dalirsani et al. Iran J Otorhinolaryngol. 2020 Sep.

Abstract

Introduction: Colon adenocarcinoma is one of the foremost causes of cancer mortality. Oral metastasis of colon adenocarcinoma is, however, rare and indicates an end-stage disease process.

Case report: We report a case of a 69-year-old female with a gingival mass diagnosed with colon adenocarcinoma and liver metastasis after one year. A swelling was found in the maxillary right buccal and lingual gingiva during physical examination. Tissue biopsy revealed an intestinal metastatic adenocarcinoma. The patient underwent chemotherapy for treatment. We also reviewed all reported cases of gingival metastasis due to colon adenocarcinoma.

Conclusion: Careful examination of the oral cavity in patients with the adenocarcinomas of various organs is beneficial in the early diagnosis of metastasis since the most frequent metastatic lesion of the oral cavity is adenocarcinoma.

Keywords: Adenocarcinoma; Colon; Gingiva; Metastasis; Oral diagnosis.

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Figures

Fig1
Fig1
Clinical appearance of the lesion; A: Granular exophytic lesion on maxillary gingiva extended from right canine to second premolar,B: extention of the lesion to palatal interdental papillas.
Fig 2
Fig 2
No osteolytic lesion on radiography
Fig 3
Fig 3
(A-B) Photomicrograph of the gingival metastatic lesion; H&E staining,100x and 400x magnification.(C-D) CK20 marker expression; IHC, 40x and 10xmagnification. (E-F) CDX2 marker expression; IHC, 40x and 10x magnification
See this image and copyright information in PMC

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